Unveiling the groove binding mechanism of a biocompatible naphthalimide-based organoselenocyanate with calf thymus DNA: an “ex vivo” fluorescence imaging …

SS Mati, SS Roy, S Chall, S Bhattacharya… - The Journal of …, 2013 - ACS Publications
The present study embodies a detailed investigation of the binding modes of a potential
anticancer and neuroprotective fluorescent drug, 2-(5-selenocyanato-pentyl)-6-chloro benzo …

Mitochondria-directed fluorescent probe for the detection of hydrogen peroxide near mitochondrial DNA

Y Wen, K Liu, H Yang, Y Liu, L Chen, Z Liu… - Analytical …, 2015 - ACS Publications
It is important to detect hydrogen peroxide (H2O2) near mitochondrial DNA (mtDNA)
because mtDNA is more prone to oxidative attack than nuclear DNA (nDNA). In this study, a …

Organotin (IV) complexes derived from Schiff base N′-[(1E)-(2-hydroxy-3-methoxyphenyl) methylidene] pyridine-4-carbohydrazone: Synthesis, in vitro cytotoxicities …

M Hong, H Geng, M Niu, F Wang, D Li, J Liu… - European journal of …, 2014 - Elsevier
Five organotin (IV) compounds were synthesized from N′-[(1E)-(2-hydroxy-3-
methoxyphenyl) methylidene] pyridine-4-carbohydrazone and the corresponding dialkyltin …

Unveiling the interaction modes of Imiquimod with DNA: Biophysical and computational studies

D Takkella, S Sharma, J Vishwakarma, J Cerezo… - … of Photochemistry and …, 2024 - Elsevier
Herein the manuscript, we report the interaction of an important drug, Imiquimod (IMQ), with
Calf Thymus Deoxyribonucleic Acid (ct-DNA). Despite of being used IMQ in multiple …

Investigating the preferential interaction between imatinib mesylate and VEGF G-quadruplex DNA as therapeutic strategies for cancer treatment: Biophysical and …

S Ghosal, S Bag, RK Chinnadurai, M Mukherjee… - Computers in Biology …, 2024 - Elsevier
Abstract G-Quadruplex DNA (GQ–DNA) is one of the most important non-canonical nucleic
acid structures. GQ–DNA forming sequences are present in different crucial genomic …

Synthesis, DNA Binding Properties, Molecular Docking and ADME Studies of Schiff Base Compound Containing Pyridine‐Propargyl Group

SA Güngör - Chemistry & Biodiversity, 2023 - Wiley Online Library
The structure of the pyridine‐based Schiff base compound containing the propargyl group
was characterized by NMR spectroscopy. Binding of compound 2 with double‐stranded fish …

Unraveling multiple binding modes of acridine orange to DNA using a multispectroscopic approach

M Sayed, B Krishnamurthy, H Pal - Physical Chemistry Chemical …, 2016 - pubs.rsc.org
The interaction of acridine orange (AOH+) with calf thymus DNA (ct-DNA) under different dye–
DNA conditions has been investigated in detail using multispectroscopic techniques …

Design, synthesis, DNA binding studies and evaluation of anticancer potential of novel substituted biscarbazole derivatives against human glioma U87 MG cell line

N Kumar, N Lal, V Nemaysh, PM Luthra - Bioorganic Chemistry, 2020 - Elsevier
In this research paper, we report the design and synthesis of novel substituted biscarbazole
derivatives which were characterized by 1 H and 13 C NMR, high resolution mass …

Exploring the preferential interaction of quercetin with VEGF promoter G-quadruplex DNA and construction of a pH-dependent DNA-based logic gate

S Bhattacharjee, PK Sengupta, S Bhowmik - RSC Advances, 2017 - pubs.rsc.org
G-Quadruplex DNA (G4–DNA) is one of the most important non-canonical nucleic acid
structures. G4–DNA forming sequences are present in different crucial genomic regions and …

Deciphering the mechanism of interaction of edifenphos with calf thymus DNA

A Ahmad, M Ahmad - Spectrochimica Acta Part A: Molecular and …, 2018 - Elsevier
Edifenphos is an important organophosphate pesticide with many antifungal and anti-
insecticidal properties but it may cause potential hazards to human health. In this work, we …