Infections with flaviviruses, such as dengue, West Nile virus and the recently re-emerging
Zika virus, are an increasing and probably lasting global risk. This Review summarizes and …

The recently emerged SARS-CoV-2 is the cause of the global health crisis of the coronavirus
disease 2019 (COVID-19) pandemic. No evidence is yet available for CoV infection into …

The emergence of the coronavirus disease 2019 (COVID-19) pandemic caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created the need for …

COVID-19 disease have become so far the most important sanitary crisis in the XXI century.
In light of the events, any clinical resource should be considered to alleviate this crisis …

Highlights•SARS-CoV-2's high homology with SARS-CoV did not prove beneficial
immediately.•Targeting viral attachment and fusion proteins has yielded good early …

ABSTRACT C3A is a subclone of the human hepatoblastoma HepG2 cell line with strong
contact inhibition of growth. We fortuitously found that C3A was more susceptible to human …

Most enveloped viruses rely on the host cell endoplasmic reticulum (ER) quality control (QC)
machinery for proper folding of glycoproteins. The key ER α-glucosidases (α-Glu) I and II of …

Direct‐acting antiviral agents (DAAs) represent a class of drugs targeting viral proteins and
have been demonstrated to be very successful in combating viral infections in clinic …

The current COVID-19 pandemic is caused by SARS CoV-2. To date,∼ 463,000 people
died worldwide due to this disease. Several attempts have been taken in search of effective …

There are large between‐and within‐country variations in COVID‐19 death rates. Some very
low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a …