Almost 60 years have passed since the initial discovery by Hubel and Wiesel that changes
in neuronal activity can elicit developmental rewiring of the central nervous system (CNS) …

LTP and LTD, the long-term potentiation and depression of excitatory synaptic transmission,
are widespread phenomena expressed at possibly every excitatory synapse in the …

In young animals, monocular deprivation leads to an ocular dominance shift, whereas in
adults after the critical period there is no such shift. Chondroitin sulphate proteoglycans …

Homeostatic synaptic scaling is a form of synaptic plasticity that adjusts the strength of all of
a neuron's excitatory synapses up or down to stabilize firing. Current evidence suggests that …

The strength of the connection between two neurons can be modified by activity, in a way
that depends on the timing of neuronal firing on either side of the synapse,,,,,,,,,. This spike …

Get in-depth understanding of each part of visual pathway yields insights to conquer the
challenges that classic computer vision is facing. Here, we first report the bioinspired striate …

Maintaining the proper balance between excitation and inhibition is critical for the normal
function of cortical circuits. This balance is thought to be maintained by an array of …

Sensory experience and learning alter sensory representations in cerebral cortex. The
synaptic mechanisms underlying sensory cortical plasticity have long been sought. Recent …

Homeostatic mechanisms stabilize neuronal activity in vivo, but whether this process gives
rise to balanced network dynamics is unknown. Here, we continuously monitored the …

Experience-dependent plasticity in somatosensory (S1) and visual (V1) cortex involves rapid
depression of responses to a deprived sensory input (a closed eye or a trimmed whisker) …