Evolving understanding of the epidemiology of thyroid cancer

CD Seib, JA Sosa - Endocrinology and Metabolism Clinics, 2019 - endo.theclinics.com
Thyroid cancer is the most common endocrine malignancy and the fastest increasing cancer
in the United States. 1 It is more common in women, with a 3: 1 female-to-male ratio in most …

Obesity and thyroid cancer risk: an update

F Franchini, G Palatucci, A Colao, P Ungaro… - International journal of …, 2022 - mdpi.com
Thyroid cancer (TC) is the most common endocrine malignancy worldwide and its incidence
has increased dramatically in recent years. In parallel, the prevalence of overweight and …

Nutritional status and follicular-derived thyroid cancer: An update

L Barrea, M Gallo, RM Ruggeri… - Critical reviews in …, 2021 - Taylor & Francis
The incidence of differentiated thyroid cancer has been increasing in the last decades all
over the world. Such a steady growth cannot be entirely attributable to more intensive thyroid …

Insulin receptor isoforms in cancer

V Vella, A Milluzzo, NM Scalisi, P Vigneri… - International journal of …, 2018 - mdpi.com
The insulin receptor (IR) mediates both metabolic and mitogenic effects especially when
overexpressed or in clinical conditions with compensatory hyperinsulinemia, due to the …

Subclinical hypothyroidism increases insulin resistance in normoglycemic people

W Yang, C **, H Wang, Y Lai, J Li… - Frontiers in Endocrinology, 2023 - frontiersin.org
Objective To investigate the effect of simple subclinical hypothyroidism (SCH) and type 2
diabetes mellitus (T2DM) combined with SCH on insulin resistance. Design and methods A …

Metabolic syndrome and thyroid Cancer: risk, prognosis, and mechanism

LR Li, JL Song, HQ Liu, C Chen - Discover Oncology, 2023 - Springer
The increasing incidence of thyroid cancer (TC) cannot be fully explained by overdiagnosis.
Metabolic syndrome (Met S) is highly prevalent due to the modern lifestyle, which can lead …

Drug repositioning in thyroid cancer treatment: the intriguing case of anti-diabetic drugs

A Greco, F Coperchini, L Croce, F Magri… - Frontiers in …, 2023 - frontiersin.org
Cancer represents the main cause of death worldwide. Thyroid cancer (TC) shows an
overall good rate of survival, however there is a percentage of patients that do not respond …

Triglycerides and glucose index as an insulin resistance marker in a sample of healthy adults

CJ Toro-Huamanchumo, D Urrunaga-Pastor… - Diabetes & Metabolic …, 2019 - Elsevier
Aim To assess the association between elevated triglycerides/glucose index (TGI) and
insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in a …

The emerging role of insulin receptor isoforms in thyroid cancer: clinical implications and new perspectives

V Vella, R Malaguarnera - International journal of molecular sciences, 2018 - mdpi.com
Thyroid cancer (TC) is the most common endocrine tumor. Although the majority of TCs
show good prognoses, a minor proportion are aggressive and refractory to conventional …

Adherence to the Mediterranean diet as a modifiable risk factor for thyroid nodular disease and thyroid cancer: Results from a pilot study

L Barrea, G Muscogiuri, G Alteriis, T Porcelli… - Frontiers in …, 2022 - frontiersin.org
Iodine deficiency is the most important established nutritional risk factor for the development
of thyroid nodular disease. Nevertheless, to the best of our knowledge, to date no study …