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The mechanism of hyperglycemia-induced renal cell injury in diabetic nephropathy disease: an update
T Wu, L Ding, V Andoh, J Zhang, L Chen - Life, 2023 - mdpi.com
Diabetic Nephropathy (DN) is a serious complication of type I and II diabetes. It develops
from the initial microproteinuria to end-stage renal failure. The main initiator for DN is chronic …
from the initial microproteinuria to end-stage renal failure. The main initiator for DN is chronic …
Carbon dot therapeutic platforms: administration, distribution, metabolism, excretion, toxicity, and therapeutic potential
Ultrasmall nanoparticles are often grouped under the broad umbrella term of “nanoparticles”
when reported in the literature. However, for biomedical applications, their small sizes give …
when reported in the literature. However, for biomedical applications, their small sizes give …
Molecular mechanisms in early diabetic kidney disease: glomerular endothelial cell dysfunction
E Lassén, IS Daehn - International journal of molecular sciences, 2020 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD), with
prevalence increasing at an alarming rate worldwide and today, there are no known cures …
prevalence increasing at an alarming rate worldwide and today, there are no known cures …
[HTML][HTML] Interplay of immune and kidney resident cells in the formation of tertiary lymphoid structures in lupus nephritis
Kidney involvement confers significant morbidity and mortality in patients with systemic
lupus erythematosus (SLE). The pathogenesis of lupus nephritis (LN) involves diverse …
lupus erythematosus (SLE). The pathogenesis of lupus nephritis (LN) involves diverse …
[HTML][HTML] Broadening horizons in mechanisms, management, and treatment of diabetic kidney disease
Diabetic kidney disease (DKD) is the first cause of end-stage kidney disease in patients with
diabetes and its prevalence is increasing worldwide. It encompasses histological alterations …
diabetes and its prevalence is increasing worldwide. It encompasses histological alterations …
Recent advances in the pharmacological applications and liver toxicity of triptolide
D Cui, D Xu, S Yue, C Yan, W Liu, R Fu, W Ma… - Chemico-Biological …, 2023 - Elsevier
Triptolide is a predominant active component of Triptergium wilfordii Hook. F, which has
been used for the treatment of cancers and autoimmune diseases such as rheumatoid …
been used for the treatment of cancers and autoimmune diseases such as rheumatoid …
Targeting inflammation for the treatment of Diabetic Kidney Disease: a five-compartment mechanistic model
A Hofherr, J Williams, LM Gan, M Söderberg… - BMC nephrology, 2022 - Springer
Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide. Mortality
and morbidity associated with DKD are increasing with the global prevalence of type 2 …
and morbidity associated with DKD are increasing with the global prevalence of type 2 …
[HTML][HTML] Therapeutic potential of pro-resolving mediators in diabetic kidney disease
Renal microvascular disease associated with diabetes [Diabetic kidney disease-DKD] is the
leading cause of chronic kidney disease. In DKD, glomerular basement membrane …
leading cause of chronic kidney disease. In DKD, glomerular basement membrane …
A review of medicinal plants with renoprotective activity in diabetic nephropathy animal models
Diabetic nephropathy (DN), also recognized as diabetic kidney disease, is a kidney
malfunction caused by diabetes mellitus. A possible contributing factor to the onset of DN is …
malfunction caused by diabetes mellitus. A possible contributing factor to the onset of DN is …
[HTML][HTML] Autophagy dysregulation in diabetic kidney disease: from pathophysiology to pharmacological interventions
CD Gonzalez, MP Carro Negueruela… - Cells, 2021 - mdpi.com
Diabetic kidney disease (DKD) is a frequent, potentially devastating complication of diabetes
mellitus. Several factors are involved in its pathophysiology. At a cellular level, diabetic …
mellitus. Several factors are involved in its pathophysiology. At a cellular level, diabetic …