Studies that examined white matter (WM) alterations in amnestic mild cognitive impairment
(aMCI) abound. This timely meta-analysis aims to synthesize the results of these studies …

Recently, the field of Alzheimer's disease (AD) research has adopted a new framework that
places the progression of AD along a continuum consisting of a preclinical stage, followed …

In this work we use non-negative matrix factorization to identify patterns of microstructural
variance in the human hippocampus. We utilize high-resolution structural and diffusion …

White matter degradation has been proposed as one possible explanation for age-related
cognitive decline. In the present study, we examined 2 main questions: 1) Do diffusion …

Specific brain structures (gray matter regions and white matter tracts) play a dominant role in
determining cognitive decline and explain the heterogeneity in cognitive aging. Identification …

Neuroimaging technique is a powerful tool to characterize the abnormality of brain networks
in schizophrenia. However, the neurophysiological substrate of schizophrenia is still …

Early diagnosis of mild cognitive impairment (MCI) fascinates screening high-risk
Alzheimer's disease (AD). White matter is found to degenerate earlier than gray matter and …

Background: Anesthesia and/or surgery accelerate Alzheimer's disease pathology and
cause memory deficits in animal models, yet there is a lack of prospective data comparing …

In human Alzheimer's disease (AD) patients and AD mouse models, both differential pre-
disease brain features and differential disease-associated memory decline are observed …

Objective: Extensive research using water-diffusion MRI reported age-related modifications
of cerebral White Matter (WM). Moreover, water-diffusion parameter modifications have been …