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[HTML][HTML] The role of cAMP in beta cell stimulus–secretion and intercellular coupling
Pancreatic beta cells secrete insulin in response to stimulation with glucose and other
nutrients, and impaired insulin secretion plays a central role in development of diabetes …
nutrients, and impaired insulin secretion plays a central role in development of diabetes …
From isles of Königsberg to islets of Langerhans: examining the function of the endocrine pancreas through network science
Islets of Langerhans are multicellular microorgans located in the pancreas that play a central
role in whole-body energy homeostasis. Through secretion of insulin and other hormones …
role in whole-body energy homeostasis. Through secretion of insulin and other hormones …
The pancreatic ß-cell response to secretory demands and adaption to stress
Pancreatic β cells dedicate much of their protein translation capacity to producing insulin to
maintain glucose homeostasis. In response to increased secretory demand, β cells can …
maintain glucose homeostasis. In response to increased secretory demand, β cells can …
[HTML][HTML] Dual mode of action of acetylcholine on cytosolic calcium oscillations in pancreatic beta and acinar cells in situ
Cholinergic innervation in the pancreas controls both the release of digestive enzymes to
support the intestinal digestion and absorption, as well as insulin release to promote nutrient …
support the intestinal digestion and absorption, as well as insulin release to promote nutrient …
Physiological levels of adrenaline fail to stop pancreatic beta cell activity at unphysiologically high glucose levels
N Sluga, L Križančić Bombek, J Kerčmar… - Frontiers in …, 2022 - frontiersin.org
Adrenaline inhibits insulin secretion from pancreatic beta cells to allow an organism to cover
immediate energy needs by unlocking internal nutrient reserves. The stimulation of α2 …
immediate energy needs by unlocking internal nutrient reserves. The stimulation of α2 …
pH-dependence of glucose-dependent activity of beta cell networks in acute mouse pancreatic tissue slice
Extracellular pH has the potential to affect various aspects of the pancreatic beta cell
function. To explain this effect, a number of mechanisms was proposed involving both …
function. To explain this effect, a number of mechanisms was proposed involving both …