Haloacid dehalogenases of Rhizobium sp. and related enzymes: Catalytic properties and mechanistic analysis

A Adamu, RA Wahab, F Aliyu, AH Aminu… - Process …, 2020 - Elsevier
Haloacid dehalogenases catalyse the cleavage of carbon− halogen bonds in halogenated
organic acids. These enzymes are of high interest due to their potential applications in …

Mini review: advances in 2-haloacid dehalogenases

Y Wang, Q **ang, Q Zhou, J Xu, D Pei - Frontiers in Microbiology, 2021 - frontiersin.org
The 2-haloacid dehalogenases (EC 3.8. 1. X) are industrially important enzymes that
catalyze the cleavage of carbon–halogen bonds in 2-haloalkanoic acids, releasing halogen …

Molecular docking and molecular dynamics simulation of Bacillus thuringiensis dehalogenase against haloacids, haloacetates and chlorpyrifos

HA Oyewusi, F Huyop, RA Wahab - Journal of Biomolecular …, 2022 - Taylor & Francis
The high dependency and surplus use of agrochemical products have liberated enormous
quantities of toxic halogenated pollutants into the environment and threaten the well-being …

In silico assessment of dehalogenase from Bacillus thuringiensis H2 in relation to its salinity-stability and pollutants degradation

HA Oyewusi, F Huyop, RA Wahab… - Journal of Biomolecular …, 2022 - Taylor & Francis
Increased scientific interest has led to the rise in biotechnological uses of halophilic and
halotolerant microbes for hypersaline wastewater bioremediation. Hence, this study …

Biodegradation of 3-chloropropionic acid (3-CP) by Bacillus cereus WH2 and its in silico enzyme-substrate docking analysis

WH Muslem, MF Edbeib, HM Aksoy… - Journal of …, 2020 - Taylor & Francis
The particular disturbing elevated presence of xenobiotic compounds viz. herbicides,
insecticides, fungicides and solvents in the environment, is the result of their widening use …

In silico mutation on a mutant lipase from Acinetobacter haemolyticus towards enhancing alkaline stability

NFSK Anuar, RA Wahab, F Huyop… - Journal of …, 2020 - Taylor & Francis
Alkaline-stable lipases are highly valuable biocatalysts that catalyze reactions under highly
basic conditions. Herein, computational predictions of lipase from Acinetobacter …

In silico targeting breast cancer biomarkers by applying rambutan (Nephelium lappaceum) phytocompounds

S Parvizpour, A Elengoe, E Alizadeh… - Journal of …, 2023 - Taylor & Francis
Worldwide, breast cancer is the leading type of cancer among women. Overexpression of
various prognostic indicators, including nuclear receptors, is linked to breast cancer …

Further analysis of Burkholderia pseudomallei MF2 and identification of putative dehalogenase gene by PCR

MF Edbeib, RA Wahab, FZ Huyop… - Indonesian Journal of …, 2020 - journal.ugm.ac.id
Halogenated organic compounds are extensively and widely used as pesticides, herbicides,
and antibiotics that contribute to the pollution. This research was aimed to further analyze …

Haloadaptation: insights from comparative modeling studies between halotolerant and non-halotolerant dehalogenases

MF Edbeib, HM Aksoy, Y Kaya… - Journal of …, 2020 - Taylor & Francis
Halophiles are extremophilic microorganisms that grow optimally at high salt concentrations
by producing a myriad of equally halotolerant enzymes. Structural haloadaptation of these …

A 2,2-dichloropropionic acid-degrading novel Pseudomonas fluorescence strain fatsa001: isolation, identification, and characterization

U Binboga Meral, MF Edbeib… - Bioremediation …, 2024 - Taylor & Francis
There are mounting concerns over the high concentrations of non-biogenic, toxic
halogenated organic compounds being liberated into the ecosystem. Therefore, this study's …