Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence

PJ Wittkopp, G Kalay - Nature Reviews Genetics, 2012 - nature.com
Cis-regulatory sequences, such as enhancers and promoters, control development and
physiology by regulating gene expression. Mutations that affect the function of these …

The evolution of gene expression in cis and trans

SA Signor, SV Nuzhdin - Trends in Genetics, 2018 - cell.com
There is abundant variation in gene expression between individuals, populations, and
species. The evolution of gene regulation and expression within and between species is …

Hybridization and speciation

R Abbott, D Albach, S Ansell, JW Arntzen… - Journal of …, 2013 - academic.oup.com
Hybridization has many and varied impacts on the process of speciation. Hybridization may
slow or reverse differentiation by allowing gene flow and recombination. It may accelerate …

Deep learning suggests that gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure

J Zrimec, CS Börlin, F Buric, AS Muhammad… - Nature …, 2020 - nature.com
Understanding the genetic regulatory code governing gene expression is an important
challenge in molecular biology. However, how individual coding and non-coding regions of …

Genomic and epigenetic insights into the molecular bases of heterosis

ZJ Chen - Nature Reviews Genetics, 2013 - nature.com
Heterosis, also known as hybrid vigour, is widespread in plants and animals, but the
molecular bases for this phenomenon remain elusive. Recent studies in hybrids and …

Evolution and origin of bread wheat

AA Levy, M Feldman - The Plant Cell, 2022 - academic.oup.com
Bread wheat (Triticum aestivum, genome BBAADD) is a young hexaploid species formed
only 8,500–9,000 years ago through hybridization between a domesticated free-threshing …

Gene balance hypothesis: connecting issues of dosage sensitivity across biological disciplines

JA Birchler, RA Veitia - Proceedings of the National Academy of Sciences, 2012 - pnas.org
We summarize, in this review, the evidence that genomic balance influences gene
expression, quantitative traits, dosage compensation, aneuploid syndromes, population …

[HTML][HTML] An evolutionarily conserved mechanism for controlling the efficiency of protein translation

T Tuller, A Carmi, K Vestsigian, S Navon, Y Dorfan… - Cell, 2010 - cell.com
Recent years have seen intensive progress in measuring protein translation. However, the
contributions of coding sequences to the efficiency of the process remain unclear. Here, we …

Comparative studies of gene expression and the evolution of gene regulation

IG Romero, I Ruvinsky, Y Gilad - Nature Reviews Genetics, 2012 - nature.com
The hypothesis that differences in gene regulation have an important role in speciation and
adaptation is more than 40 years old. With the advent of new sequencing technologies, we …

Heterosis

JA Birchler, H Yao, S Chudalayandi, D Vaiman… - The Plant …, 2010 - academic.oup.com
Heterosis refers to the phenomenon that progeny of diverse varieties of a species or crosses
between species exhibit greater biomass, speed of development, and fertility than both …