Treatment of severe COVID-19 is currently limited by clinical heterogeneity and incomplete
description of specific immune biomarkers. We present here a comprehensive multi-omic …

Pronounced immune escape by the SARS-CoV-2 Omicron variant has resulted in many
individuals possessing hybrid immunity, generated through a combination of vaccination …

Adaptive immune receptor repertoires (AIRR) are key targets for biomedical research as
they record past and ongoing adaptive immune responses. The capacity of machine …

COVID-19 is characterized by a broad range of symptoms and disease trajectories.
Understanding the correlation between clinical biomarkers and lung pathology during acute …

Artificial intelligence (AI) techniques are increasingly applied across various domains,
favoured by the growing acquisition and public availability of large, complex datasets …

Understanding protective influenza immunity and identifying immune correlates of protection
poses a major challenge and requires an appreciation of the immune system in all of its …

The trajectories of acquired immunity to severe acute respiratory syndrome coronavirus 2
infection are not fully understood. We present a detailed longitudinal cohort study of UK …

The field of protein data mining has been growing rapidly in the last years. To characterize
proteins and determine their function from their amino acid sequences are challenging and …

The worldwide COVID-19 pandemic has claimed millions of lives and has had a profound
effect on global life. Understanding the body's immune response to SARS-CoV-2 infection is …

Linking clinical biomarkers and lung pathology still is necessary to understand COVID-19
pathogenesis and the basis of progression to lethal outcomes. Resolving these knowledge …