Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …

Accurate in vivo imaging of G-quadruplexes (G4) is critical for understanding the emergence
and progression of G4-associated diseases like cancer. However, existing in vivo G4 …

The viscosity and crowding of biological environment are considered vital for the correct
cellular function, and alterations in these parameters are known to underly a number of …

Substantial evidence now exists to support that formation of DNA G-quadruplexes (G4s) is
coupled to altered gene expression. However, approaches that allow us to probe G4s in …

Metazoan promoters are enriched in secondary DNA structure-forming motifs, such as G-
quadruplexes (G4s). Here we describe 'G4access', an approach to isolate and sequence …

RNA molecules can fold into intricate shapes that can provide an additional layer of control
of gene expression beyond that of their sequence. In this Review, we discuss the current …

Genomic maps of DNA G-quadruplexes (G4s) can help elucidate the roles that these
secondary structures play in various organisms. Herein, we employ an improved version of a …

A curated library of circular dichroism spectra of 23 G‐quadruplexes of known structure was
built and analyzed. The goal of this study was to use this reference library to develop an …

In addition to the canonical right-handed double helix, other DNA structures, termed 'non-B
DNA', can form in the genomes across the tree of life. Non-B DNA regulates multiple cellular …