[HTML][HTML] Antiplatelet and anticoagulation strategies for left ventricular assist devices

RY Loyaga-Rendon, T Kazui… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Left ventricular assist devices (LVAD) have revolutionized the management of advanced
heart failure. However, complications rates remain high, among which hemorrhagic and …

Multi-indicator analysis of mechanical blood damage with five clinical ventricular assist devices

Y Li, H Wang, Y **, A Sun, X Deng, Z Chen… - Computers in biology and …, 2022 - Elsevier
Purpose Device-induced blood damage contributes the hemolysis, thrombosis and bleeding
complications in patients supported with ventricular assist device (VAD). This study aims to …

Developments and Challenges in Durable Ventricular Assist Device Technology: A Comprehensive Review with a Focus on Advancements in China

J Tu, L Xu, F Li, N Dong - Journal of Cardiovascular Development and …, 2024 - mdpi.com
Heart transplantation is currently the most effective treatment for end-stage heart failure;
however, the shortage in donor hearts constrains the undertaking of transplantation …

Computational characterization of flow and blood damage potential of the new maglev CH-VAD pump versus the HVAD and HeartMate II pumps

J Zhang, Z Chen, BP Griffith… - The International journal …, 2020 - journals.sagepub.com
Left ventricular assist devices are routinely used to treat patients with advanced heart failure
as a bridge to transplant or a destination therapy. However, non-physiological shear stress …

A new mathematical numerical model to evaluate the risk of thrombosis in three clinical ventricular assist devices

Y Li, H Wang, Y **, A Sun, X Deng, Z Chen, Y Fan - Bioengineering, 2022 - mdpi.com
(1) Background: Thrombosis is the main complication in patients supported with ventricular
assist devices (VAD). Models that accurately predict the risk of thrombus formation in VADs …

[HTML][HTML] A new way to evaluate thrombotic risk in failure heart and ventricular assist devices

Y Li, Y **, H Wang, A Sun, X Deng, Z Chen… - Medicine in Novel …, 2022 - Elsevier
Thrombosis is one of the main complications in patients implanted with ventricular assist
device (VAD). The complicated structure and disturbed flow field within failure heart and …

Impact of high mechanical shear stress and oxygenator membrane surface on blood damage relevant to thrombosis and bleeding in a pediatric ECMO circuit

W Sun, S Wang, Z Chen, J Zhang, T Li, K Arias… - Artificial …, 2020 - Wiley Online Library
The roles of the large membrane surface of the oxygenator and the high mechanical shear
stress (HMSS) of the pump in the extracorporeal membrane oxygenation (ECMO) circuit …

Comprehensive study on simulation, performance evaluation and optimization strategies for blood pumps

Y Li, H Wang, X Liu, Y **, A Sun, L Wang… - Engineering …, 2024 - Taylor & Francis
This study aims to develop simulation methods, performance evaluation methods, and
optimization strategies for blood pumps. Computational fluid dynamics, in-vitro …

Prediction of mechanical hemolysis in medical devices via a Lagrangian strain‐based multiscale model

M Nikfar, M Razizadeh, J Zhang, R Paul, ZJ Wu… - Artificial …, 2020 - Wiley Online Library
This work introduces a new Lagrangian strain‐based model to predict the shear‐induced
hemolysis in biomedical devices. Current computational models for device‐induced …

[HTML][HTML] Computational fluid dynamics analysis and experimental hemolytic performance of three clinical centrifugal blood pumps: Revolution, Rotaflow and …

D Han, JL Leibowitz, L Han, S Wang, G He… - Medicine in novel …, 2022 - Elsevier
Centrifugal blood pumps have become popular for adult extracorporeal membrane
oxygenation (ECMO) due to their superior blood handling and reduced thrombosis risk …