Circulating tumour DNA alterations: emerging biomarker in head and neck squamous cell carcinoma
Head and Neck cancers (HNC) are a heterogeneous group of upper aero-digestive tract
cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of …
cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of …
[HTML][HTML] HPV and head and neck cancers: Towards early diagnosis and prevention
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide with an increasing trend of its incidence. Alcohol consumption, smoking, and viral …
worldwide with an increasing trend of its incidence. Alcohol consumption, smoking, and viral …
Plasma circulating tumor HPV DNA for the surveillance of cancer recurrence in HPV-associated oropharyngeal cancer
PURPOSE Plasma circulating tumor human papillomavirus DNA (ctHPVDNA) is a sensitive
and specific biomarker of human papillomavirus (HPV)-associated oropharyngeal …
and specific biomarker of human papillomavirus (HPV)-associated oropharyngeal …
Detection of occult recurrence using circulating tumor tissue modified viral HPV DNA among patients treated for HPV-driven oropharyngeal carcinoma
Purpose: Despite generally favorable outcomes, 15% to 25% of patients with human
papillomavirus (HPV)-driven oropharyngeal squamous cell carcinoma (OPSCC) will have …
papillomavirus (HPV)-driven oropharyngeal squamous cell carcinoma (OPSCC) will have …
Liquid BIOpsy for MiNimal RESidual DiSease Detection in Head and Neck Squamous Cell Carcinoma (LIONESS)—a personalised circulating tumour DNA analysis in …
S Flach, K Howarth, S Hackinger, C Pipinikas… - British Journal of …, 2022 - nature.com
Background Head and neck squamous cell carcinoma (HNSCC) remain a substantial
burden to global health. Cell-free circulating tumour DNA (ctDNA) is an emerging biomarker …
burden to global health. Cell-free circulating tumour DNA (ctDNA) is an emerging biomarker …
Cell-free HPV DNA provides an accurate and rapid diagnosis of HPV-associated head and neck cancer
G Siravegna, CJ O'Boyle, S Varmeh, N Queenan… - Clinical Cancer …, 2022 - AACR
Purpose: HPV-associated head and neck squamous cell carcinoma (HPV+ HNSCC) is the
most common HPV-associated malignancy in the United States and continues to increase in …
most common HPV-associated malignancy in the United States and continues to increase in …
Cell‐free human papillomavirus DNA kinetics after surgery for human papillomavirus–associated oropharyngeal cancer
CJ O'Boyle, G Siravegna, S Varmeh, N Queenan… - Cancer, 2022 - Wiley Online Library
Background New ultrasensitive methods for detecting residual disease after surgery are
needed in human papillomavirus–associated oropharyngeal squamous cell carcinoma …
needed in human papillomavirus–associated oropharyngeal squamous cell carcinoma …
Early HPV ctDNA kinetics and imaging biomarkers predict therapeutic response in p16+ oropharyngeal squamous cell carcinoma
Purpose: In locally advanced p16+ oropharyngeal squamous cell carcinoma (OPSCC),(i) to
investigate kinetics of human papillomavirus (HPV) circulating tumor DNA (ctDNA) and …
investigate kinetics of human papillomavirus (HPV) circulating tumor DNA (ctDNA) and …
HPV sequencing facilitates ultrasensitive detection of HPV circulating tumor DNA
Abstract Purpose: Human papillomavirus (HPV) DNA offers a convenient circulating tumor
DNA (ctDNA) marker for HPV-associated malignancies, but current methods, such as digital …
DNA (ctDNA) marker for HPV-associated malignancies, but current methods, such as digital …
Analytical validation of NavDx, a cfDNA-based fragmentomic profiling assay for HPV-driven cancers
A Gunning, S Kumar, CK Williams, BM Berger… - Diagnostics, 2023 - mdpi.com
The NavDx® blood test analyzes tumor tissue modified viral (TTMV)-HPV DNA to provide a
reliable means of detecting and monitoring HPV-driven cancers. The test has been clinically …
reliable means of detecting and monitoring HPV-driven cancers. The test has been clinically …