EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility

NE Skakkebaek, E Rajpert-De Meyts… - Physiological …, 2016 - journals.physiology.org
It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …

Human germ cell tumours from a developmental perspective

JW Oosterhuis, LHJ Looijenga - Nature Reviews Cancer, 2019 - nature.com
Human germ cell tumours (GCTs) are derived from stem cells of the early embryo and the
germ line. They occur in the gonads (ovaries and testes) and also in extragonadal sites …

Disorders of spermatogenesis: perspectives for novel genetic diagnostics after 20 years of unchanged routine

F Tüttelmann, C Ruckert, A Röpke - Medizinische Genetik, 2018 - degruyter.com
Infertility is a common condition estimated to affect 10–15% of couples. The clinical causes
are attributed in equal parts to the male and female partners. Diagnosing male infertility …

Testicular cancer—discoveries and updates

NH Hanna, LH Einhorn - New England Journal of Medicine, 2014 - Mass Medical Soc
Testicular Cancer — Discoveries and Updates | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Testicular cancer: epidemiology, diagnosis, and management

ZL Smith, RP Werntz, SE Eggener - Medical Clinics, 2018 - medical.theclinics.com
In 2016, there were an estimated 8700 new cases of testicular cancer (TC) in the United
States and 380 deaths. 1 Although TC is a rare disease, accounting for only approximately …

Testicular germ cell tumor: a comprehensive review

A Batool, N Karimi, XN Wu, SR Chen, YX Liu - Cellular and Molecular Life …, 2019 - Springer
Testicular tumors are the most common tumors in adolescent and young men and germ cell
tumors (TGCTs) account for most of all testicular cancers. Increasing incidence of TGCTs …

[HTML][HTML] Genetics of cryptorchidism and testicular regression

HP Elamo, HE Virtanen, J Toppari - Best Practice & Research Clinical …, 2022 - Elsevier
Cryptorchidism, ie, undescended testis, is one of the most common genital malformations in
newborn male babies. The birth rate of cryptorchidism varies from 1.6 to 9.0%. Etiology of …

Testicular cancer and cryptorchidism

L Ferguson, AI Agoulnik - Frontiers in endocrinology, 2013 - frontiersin.org
The failure of testicular descent or cryptorchidism is the most common defect in newborn
boys. The descent of the testes during development is controlled by insulin-like 3 peptide …

[HTML][HTML] Testicular cancer incidence to rise by 25% by 2025 in Europe? Model-based predictions in 40 countries using population-based registry data

C Le Cornet, J Lortet-Tieulent, D Forman… - European journal of …, 2014 - Elsevier
Background Testicular cancer mainly affects White Caucasian populations, accounts for 1%
of all male cancers, and is frequently the most common malignancy among young adult …