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Hydrazide-hydrazone/hydrazone as enabling linkers in anti-cancer drug discovery: A comprehensive review
S Murugappan, S Dastari, K Jungare, NM Barve… - Journal of Molecular …, 2024 - Elsevier
The burgeoning demand for novel cytotoxic drugs possessing improved bioavailability and
safety profiles has spurred the hybridization of various pharmacophores in the past decades …
safety profiles has spurred the hybridization of various pharmacophores in the past decades …
A review of hydrazide-hydrazone metal complexes' antitumor potential
Cancer inflicts a tremendous burden on modern society, and more effective and selective
treatments need to be developed. Metallodrugs have been extensively explored as …
treatments need to be developed. Metallodrugs have been extensively explored as …
Synthetic approach toward spiro quinoxaline-β-lactam based heterocyclic compounds: Spectral characterization, SAR, pharmacokinetic and biomolecular interaction …
RA Dabhi, MP Dhaduk, VD Bhatt… - Journal of Biomolecular …, 2023 - Taylor & Francis
Abstract Series of spiro quinoxaline-β-lactam based heterocyclic compounds (QL 1–QL 21)
were synthesized and characterized by spectroscopic techniques like 1H-NMR, LC-MS, FT …
were synthesized and characterized by spectroscopic techniques like 1H-NMR, LC-MS, FT …
Copper (II) complexes incorporated with 2, 2-bipyridyl and 2, 2′-(((1E, 1′ E)-1, 4-phenylene-bis (methanylylidene)) bis (azanylylidene)) diphenol derivatives: In-vitro …
SV Salimath, M Pathak - Inorganic Chemistry Communications, 2024 - Elsevier
Certain metal complexes have created their own benchmark in the category of cytotoxic
drugs. Down the line, copper metal complexes are found among the most prominent …
drugs. Down the line, copper metal complexes are found among the most prominent …
Recent development on copper-sensor and its biological applications: A review
K Srishti, O Negi, PK Hota - Journal of Fluorescence, 2024 - Springer
Metal ion recognition is one of the most prospective research topics in the field of chemical
sensors due to its wide range of clinical, biological and environmental applications. In this …
sensors due to its wide range of clinical, biological and environmental applications. In this …
Copper (II) complexes containing hydrazone and bipyridine/phenanthroline ligands for anticancer application against breast cancer cells
In this work, mixed ligand Cu (II) complexes containing hydrazone and bipyridine ligands
(CB1-CB5), or hydrazone and phenanthroline ligands (CP1-CP5) have been synthesized …
(CB1-CB5), or hydrazone and phenanthroline ligands (CP1-CP5) have been synthesized …
Heteroleptic complexes of hydrazone Scaffold of picolinoyl N-oxide and 2, 4 dihydroxy phenyl moieties; evaluation of antioxidant activity, DNA and protein binding …
S Deepa, N Mathangi, R Mudavath, I Shekhar… - Inorganica Chimica …, 2025 - Elsevier
The present study deals with design and synthesis of new mononuclear Cu (II), Co (II), Ni (II)
and Zn (II) metal complexes of hydrazone of 2-(2-(2, 4-dihydroxybenzylidene) …
and Zn (II) metal complexes of hydrazone of 2-(2-(2, 4-dihydroxybenzylidene) …
The synthesis of novel water-soluble zinc (II) phthalocyanine based photosensitizers and exploring of photodynamic therapy activities on the PC3 cancer cell line
In this study, Schiff base substituted phthalocyanine complexes (Zn1c, Zn2c) and their
quaternized derivatives (Q-Zn1c, Q-Zn2c) were synthesized for the first time. Their structures …
quaternized derivatives (Q-Zn1c, Q-Zn2c) were synthesized for the first time. Their structures …
Evaluation of DNA and BSA-Binding, Nuclease Activity, and Anticancer Properties of New Cu (II) and Ni (II) Complexes with Quinoline-Derived Sulfonamides
Four complexes of essential metal ions, Cu (II) and Ni (II), with the new sulfonamide ligand N-
(pyridin-2-ylmethyl) quinoline-8-sulfonamide (HQSMP) were synthesized and …
(pyridin-2-ylmethyl) quinoline-8-sulfonamide (HQSMP) were synthesized and …
Interactions of novel pyrazole ligand and its transition metal complexes with CT-DNA and BSA: A combination of experimental and computational studies
N Zhang, X Liu, S Zhao, Z Yang - Polyhedron, 2023 - Elsevier
A novel pyrazole acylhydrazone (C 11 H 11 N 5 O, HL) and its four transition metal
complexes [Co (HL) L] NO 3 (C1),[Ni (HL) L] NO 3 (C2),[Cu (HL) L] NO 3 (C3),[Zn (HL) L] NO …
complexes [Co (HL) L] NO 3 (C1),[Ni (HL) L] NO 3 (C2),[Cu (HL) L] NO 3 (C3),[Zn (HL) L] NO …