Hepatic steatosis is characterized by abnormal and excessive accumulation of lipids within
hepatocytes. It is an important feature of diffuse liver disease, and the histological hallmark …

Background Magnetic resonance imaging (MRI) is the dominant 3D imaging modality to
quantify muscle properties in skeletal muscle disorders, in inherited and acquired muscle …

Purpose The purpose of this study was to develop a multi‐step adaptive fitting approach for
liver proton density fat fraction (PDFF) and quantification, and to perform an initial validation …

Iron overload is the histological hallmark of genetic hemochromatosis and transfusional
hemosiderosis but also may occur in chronic hepatopathies. This article provides an …

Quantitative water/fat separation in MRI requires careful modeling of the acquired signal.
Multiple signal models have been proposed in recent years, but their relative performance …

Accurate, noninvasive measurements of liver fat content are needed for the early diagnosis
and quantitative staging of nonalcoholic fatty liver disease. Chemical shift‐based fat …

The two‐point Dixon method is a proton chemical shift imaging technique that produces
separated water‐only and fat‐only images from a dual‐echo acquisition. It is shown how this …

OBJECTIVE. The purpose of this study was to characterize human brown adipose tissue
(BAT) with chemical-shift water-fat MRI and to determine whether trends and differences in …

R_2^∗ab map** has important applications in MRI, including functional imaging, tracking
of super‐paramagnetic particles, and measurement of tissue iron levels. However, R_2^∗ab …

OBJECTIVE. The purpose of this study is to prospectively compare hybrid and complex
chemical shift–based MRI fat quantification methods against MR spectroscopy (MRS) for the …