The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Liver ischaemia–reperfusion injury (LIRI), a local sterile inflammatory response driven by
innate immunity, is one of the primary causes of early organ dysfunction and failure after …

Physical exercise is generally beneficial to all aspects of human and animal health, slowing
cognitive ageing and neurodegeneration. The cognitive benefits of physical exercise are …

The liver is a central organ in the human body, coordinating several key metabolic roles. The
structure of the liver which consists of the distinctive arrangement of hepatocytes, hepatic …

Hepatocytes, the major parenchymal cells in the liver, are responsible for a variety of cellular
functions including carbohydrate, lipid and protein metabolism, detoxification and immune …

A pro-inflammatory intestinal microbiome is characteristic of Parkinson's disease (PD).
Prebiotic fibers change the microbiome and this study sought to understand the utility of …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, and scientific studies consistently report that NAFLD development can be …

Due to the rise in overnutrition, the incidence of obesity-induced hepatocellular carcinoma
(HCC) will continue to escalate; however, our understanding of the obesity to HCC …

Hereditary genetic disorders, cancer, and infectious diseases of the liver affect millions of
people around the globe and are a major public health burden. Most contemporary …

The human liver is usually perceived as a non-immunological organ engaged primarily in
metabolic, nutrient storage and detoxification activities. However, we now know that the …