[HTML][HTML] Machine learning applications for mass spectrometry-based metabolomics

UW Liebal, ANT Phan, M Sudhakar, K Raman… - Metabolites, 2020 - mdpi.com
The metabolome of an organism depends on environmental factors and intracellular
regulation and provides information about the physiological conditions. Metabolomics helps …

[HTML][HTML] Deep metabolome: Applications of deep learning in metabolomics

Y Pomyen, K Wanichthanarak, P Poungsombat… - Computational and …, 2020 - Elsevier
In the past few years, deep learning has been successfully applied to various omics data.
However, the applications of deep learning in metabolomics are still relatively low compared …

Recent developments along the analytical process for metabolomics workflows

C Gonzalez-Riano, D Dudzik, A Garcia… - Analytical …, 2019 - ACS Publications
We are in the midst of a shift in biological research paradigms from reductionist
methodologies that generate a hypothesis and rigorously and quantitatively measure the …

Evolutionary computation in bioinformatics: A survey

Y Zhang, L Cheng, G Chen, D Alghazzawi - Neurocomputing, 2024 - Elsevier
Bioinformatics is a subject that studies life phenomena by using mathematical and
information science theories and techniques. Its main tasks, such as DNA sequence …

Metabolomics in autoimmune diseases: focus on rheumatoid arthritis, systemic lupus erythematous, and multiple sclerosis

N Yoon, AK Jang, Y Seo, BH Jung - Metabolites, 2021 - mdpi.com
The metabolomics approach represents the last downstream phenotype and is widely used
in clinical studies and drug discovery. In this paper, we outline recent advances in the …

Metabolomics as a valid analytical technique in environmental exposure research: application and progress

S Wei, Y Wei, Y Gong, Y Chen, J Cui, L Li, H Yan, Y Yu… - Metabolomics, 2022 - Springer
Background In recent years, studies have shown that exposure to environmental pollutants
(eg, radiation, heavy metal substances, air pollutants, organic pollutants) is a leading cause …

[HTML][HTML] Predicting lameness in dairy cattle using untargeted liquid chromatography–mass spectrometry-based metabolomics and machine learning

LV Randall, DH Kim, SMA Abdelrazig, NJ Bollard… - Journal of Dairy …, 2023 - Elsevier
Lameness in dairy cattle is a highly prevalent condition that impacts on the health and
welfare of dairy cows. Prompt detection and implementation of effective treatment is …

[HTML][HTML] Discovery of a metabolic signature predisposing high risk patients with mild cognitive impairment to converting to Alzheimer's disease

YL Huang, CH Lin, TH Tsai, CH Huang, JL Li… - International journal of …, 2021 - mdpi.com
Assessing dementia conversion in patients with mild cognitive impairment (MCI) remains
challenging owing to pathological heterogeneity. While many MCI patients ultimately …

Deep learning analysis of UPLC-MS/MS-based metabolomics data to predict Alzheimer's disease

K Wang, LA Theeke, C Liao, N Wang, Y Lu… - Journal of the …, 2023 - Elsevier
Objective Metabolic biomarkers can potentially inform disease progression in Alzheimer's
disease (AD). The purpose of this study is to identify and describe a new set of diagnostic …

[HTML][HTML] Fungal Metabolomics: A Comprehensive Approach to Understanding Pathogenesis in Humans and Identifying Potential Therapeutics

V Alves, D Zamith-Miranda, S Frases, JD Nosanchuk - Journal of Fungi, 2025 - mdpi.com
Metabolomics has emerged as a transformative tool in the study of microbes, including
pathogenic fungi, facilitating the identification of unique metabolic profiles that elucidate their …