Parkinson's disease (PD) is one of the most common degenerative brain disorders caused
by the loss of dopaminergic neurons in the substantia nigra (SN). Lewy bodies and …

Methionine is an essential amino acid, involved in the promotion of growth, immunity, and
regulation of energy metabolism. Over the decades, research has long focused on the …

Homocysteine is a non-proteinogenic sulfhydryl-containing amino acid derived from
methionine and is a homologue of cysteine. The concentration of homocysteine is regulated …

Cardiovascular, rheumatic, kidney, and neurodegenerative diseases and mental disorders
are a common cause of deterioration in the quality of life up to severe disability and death …

In view of the significant role of H2S in brain functioning, it is proposed that H2S may also
possess protective effects against adverse effects of neurotoxicants. Therefore, the objective …

Homocysteine is a sulfur-containing endogenous amino acid leading to neurotoxic effects at
high concentrations. Population studies suggest an association between plasma …

Although anxiety is perhaps one of the most significant current medical and social problems,
the neurochemical mechanistic background of this common condition remains to be fully …

Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, are
immune-mediated chronic inflammatory diseases of the intestinal tract. Under conditions of …

Background. Excessive or insufficient intake of methionine (Met) causes neuronal
dysfunction, neurodegeneration, cerebrovascular dysfunction, vascular leakage, and short …

Accumulating clinical and preclinical data indicate a prominent role of gut microbiota in
regulation of physiological functions. The gut-brain axis imbalance due to gut dysbiosis is …