The Catharanthus (or Vinca) alkaloids comprise a group of about 130 terpenoid indole
alkaloids. Vinblastine is now marketed for more than 40 years as an anticancer drug and …

The production of plant secondary metabolites by means of large-scale culture of plant cells
in bioreactors is technically feasible. The economy of such a production is the major …

The drug discovery process increasingly requires the availability of large numbers of
compounds. Chemodiversity in nature offers a valuable source; for example, secondary …

Cancer is a major killer disease all over the world and more than six million new cases are
reported every year. Nature is an attractive source of new therapeutic compounds, as a …

Geraniol 10‐hydroxylase (G10H) is a cytochrome P450 monooxygenase involved in the
biosynthesis of iridoid monoterpenoids and several classes of monoterpenoid alkaloids …

The technology of large-scale plant cell culture is feasible for the industrial production of
plant-derived fine chemicals. Due to low or no productivity of the desired compounds the …

As the only source for the low-abundance antitumor agents vinblastine and vincristine,
Catharanthus roseus is highly valued and has been studied extensively as a model for …

Catharanthus roseus is still the only source for the powerful antitumour drugs vinblastine
and vincristine. Some other pharmaceutical compounds from this plant, ajmalicine and …

Plant secondary metabolism is very important for traits such as flower color, flavor of food,
and resistance against pests and diseases. Moreover, it is the source of many fine chemicals …

Medicinal plants and environmental challenges Mansour Ghorbanpour Ajit Varma Editors
Medicinal Plants and Environmental Challenges Page 2 Medicinal Plants and …