Zoonotic diseases: etiology, impact, and control

MT Rahman, MA Sobur, MS Islam, S Ievy, MJ Hossain… - Microorganisms, 2020 - mdpi.com
Most humans are in contact with animals in a way or another. A zoonotic disease is a
disease or infection that can be transmitted naturally from vertebrate animals to humans or …

SARS-CoV-2: from its discovery to genome structure, transcription, and replication

AC Brant, W Tian, V Majerciak, W Yang, ZM Zheng - Cell & bioscience, 2021 - Springer
SARS-CoV-2 is an extremely contagious respiratory virus causing adult atypical pneumonia
COVID-19 with severe acute respiratory syndrome (SARS). SARS-CoV-2 has a single …

Coronavirus disease 2019 (COVID-19): current status and future perspectives

H Li, SM Liu, XH Yu, SL Tang, CK Tang - International journal of …, 2020 - Elsevier
ABSTRACT Coronavirus disease 2019 (COVID-19) originated in the city of Wuhan, Hubei
Province, Central China, and has spread quickly to 72 countries to date. COVID-19 is …

A prenylated dsRNA sensor protects against severe COVID-19

A Wickenhagen, E Sugrue, S Lytras, S Kuchi… - Science, 2021 - science.org
INTRODUCTION Interferons (IFNs) are cytokines that are rapidly deployed in response to
invading pathogens. By initiating a signaling cascade that stimulates the expression of …

[HTML][HTML] Zoonotic origins of human coronaviruses

ZW Ye, S Yuan, KS Yuen, SY Fung… - International journal of …, 2020 - ncbi.nlm.nih.gov
Mutation and adaptation have driven the co-evolution of coronaviruses (CoVs) and their
hosts, including human beings, for thousands of years. Before 2003, two human CoVs …

[HTML][HTML] COVID-19: The first documented coronavirus pandemic in history

YC Liu, RL Kuo, SR Shih - Biomedical journal, 2020 - Elsevier
The novel human coronavirus disease COVID-19 has become the fifth documented
pandemic since the 1918 flu pandemic. COVID-19 was first reported in Wuhan, China, and …

From SARS to SARS-CoV-2, insights on structure, pathogenicity and immunity aspects of pandemic human coronaviruses

N Kirtipal, S Bharadwaj, SG Kang - Infection, Genetics and Evolution, 2020 - Elsevier
Abstract Human Coronaviruses (HCoV), periodically emerging across the world, are
potential threat to humans such as severe acute respiratory syndrome coronavirus-2 (SARS …

[HTML][HTML] Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

C Wu, Y Liu, Y Yang, P Zhang, W Zhong… - … Pharmaceutica Sinica B, 2020 - Elsevier
SARS-CoV-2 has caused tens of thousands of infections and more than one thousand
deaths. There are currently no registered therapies for treating coronavirus infections …

[HTML][HTML] SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology

NS Ogando, TJ Dalebout… - Journal of General …, 2020 - microbiologyresearch.org
The sudden emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
at the end of 2019 from the Chinese province of Hubei and its subsequent pandemic spread …

Subunit vaccines against emerging pathogenic human coronaviruses

N Wang, J Shang, S Jiang, L Du - Frontiers in microbiology, 2020 - frontiersin.org
Seven coronaviruses (CoVs) have been isolated from humans so far. Among them, three
emerging pathogenic CoVs, including severe acute respiratory syndrome coronavirus …