Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and
chloroquine in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus …
chloroquine in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus …
Novel paradigms in systemic lupus erythematosus
The heterogeneity of systemic lupus erythematosus (SLE), long recognised by clinicians, is
now challenging the entire lupus community, from geneticists to clinical investigators …
now challenging the entire lupus community, from geneticists to clinical investigators …
Hydroxychloroquine in systemic lupus erythematosus: overview of current knowledge
A Dima, C Jurcut, F Chasset… - Therapeutic …, 2022 - journals.sagepub.com
The antimalarial hydroxychloroquine (HCQ) has demonstrated several crucial properties for
the treatment of systemic lupus erythematosus (SLE). Herein, we reviewed the main HCQ …
the treatment of systemic lupus erythematosus (SLE). Herein, we reviewed the main HCQ …
An update on the management of childhood-onset systemic lupus erythematosus
Childhood-onset systemic lupus erythematosus (cSLE) is a prototype of a multisystemic,
inflammatory, heterogeneous autoimmune condition. This disease is characterized by …
inflammatory, heterogeneous autoimmune condition. This disease is characterized by …
10 Years of belimumab experience: What have we learnt?
RA Levy, T Gonzalez-Rivera, M Khamashta, NL Fox… - Lupus, 2021 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease
affecting both adults and children. Belimumab is the only biologic approved for SLE, and the …
affecting both adults and children. Belimumab is the only biologic approved for SLE, and the …
Glucocorticoids in Systemic Lupus Erythematosus. Ten Questions and Some Issues
S Porta, A Danza, M Arias Saavedra… - Journal of clinical …, 2020 - mdpi.com
Since the discovery of glucocorticoids (GCs), their important anti-inflammatory effect, rapid
mechanism of action, low cost, and accessibility have made them one of the mainstays of …
mechanism of action, low cost, and accessibility have made them one of the mainstays of …
Remission and low disease activity (LDA) prevent damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International …
MF Ugarte-Gil, J Hanly, M Urowitz, C Gordon… - Annals of the …, 2022 - ard.bmj.com
Objective To determine the independent impact of different definitions of remission and low
disease activity (LDA) on damage accrual. Methods Patients with≥ 2 annual assessments …
disease activity (LDA) on damage accrual. Methods Patients with≥ 2 annual assessments …
Systemic lupus erythematosus: state of the art on clinical practice guidelines
F Tamirou, L Arnaud, R Talarico, CA Scirè… - RMD open, 2019 - rmdopen.bmj.com
Systemic lupus erythematosus (SLE) is the paradigm of systemic autoimmune diseases
characterised by a wide spectrum of clinical manifestations with an unpredictable relapsing …
characterised by a wide spectrum of clinical manifestations with an unpredictable relapsing …
Current cell therapies for systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease in which multiple
organs are damaged by the immune system. Although standard treatment options such as …
organs are damaged by the immune system. Although standard treatment options such as …
Factors predictive of serious infections over time in systemic lupus erythematosus patients: data from a multi-ethnic, multi-national, Latin American lupus cohort
Aim The aim of this study was to identify factors predictive of serious infections over time in
patients with systemic lupus erythematosus (SLE). Methods A multi-ethnic, multi-national …
patients with systemic lupus erythematosus (SLE). Methods A multi-ethnic, multi-national …