[HTML][HTML] The global burden of sepsis and septic shock

L La Via, G Sangiorgio, S Stefani, A Marino, G Nunnari… - Epidemiologia, 2024 - mdpi.com
A dysregulated host response to infection causes organ dysfunction in sepsis and septic
shock, two potentially fatal diseases. They continue to be major worldwide health burdens …

Systemic inflammation after trauma

A Lenz, GA Franklin, WG Cheadle - Injury, 2007 - Elsevier
Trauma is still one of the main reasons for death among the population worldwide. Mortality
occurring early after injury is due to “first hits”, including severe organ injury, hypoxia …

Beyond the brain: peripheral interactions after traumatic brain injury

SJ McDonald, JM Sharkey, M Sun… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) is a leading cause of death and disability, and there are currently
no pharmacological treatments known to improve patient outcomes. Unquestionably …

Increases in mortality, length of stay, and cost associated with hospital-acquired infections in trauma patients

LG Glance, PW Stone, DB Mukamel… - Archives of surgery, 2011 - jamanetwork.com
Objective To explore the clinical impact and economic burden of hospital-acquired infections
(HAIs) in trauma patients using a nationally representative database. Design Retrospective …

Epidemiology and risk factors of sepsis after multiple trauma: an analysis of 29,829 patients from the Trauma Registry of the German Society for Trauma Surgery

A Wafaisade, R Lefering, B Bouillon… - Critical care …, 2011 - journals.lww.com
Objectives: The objectives of this study were 1) to assess potential changes in the incidence
and outcome of sepsis after multiple trauma in Germany between 1993 and 2008 and 2) to …

Frequency, causes and pattern of abdominal trauma: a 4-year descriptive analysis

S Arumugam, A Al-Hassani, A El-Menyar… - … , trauma, and shock, 2015 - journals.lww.com
Background: The incidence of abdominal trauma is still underreported from the Arab Middle-
East. We aimed to evaluate the incidence, causes, clinical presentation, and outcome of the …

Trauma, shock, and disseminated intravascular coagulation: lessons from the classical literature

S Gando, A Sawamura, M Hayakawa - Annals of surgery, 2011 - journals.lww.com
A trauma patient's survival depends on the ability to control 2 opposing conditions, bleeding
at the early phase and thrombosis at a late phase of trauma. The mixed existence of …

Traumatic brain injury and intestinal dysfunction: uncovering the neuro-enteric axis

V Bansal, T Costantini, L Kroll, C Peterson… - Journal of …, 2009 - liebertpub.com
Traumatic brain injury (TBI) can lead to several physiologic complications including
gastrointestinal dysfunction. Specifically, TBI can induce an increase in intestinal …

Hydrocortisone therapy for patients with multiple trauma: the randomized controlled HYPOLYTE study

A Roquilly, PJ Mahe, P Seguin, C Guitton, H Floch… - Jama, 2011 - jamanetwork.com
Context The role of stress-dose hydrocortisone in the management of trauma patients is
currently unknown. Objective To test the efficacy of hydrocortisone therapy in trauma …

Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems

R Sharma, SR Shultz, MJ Robinson, A Belli… - Brain, behavior, and …, 2019 - Elsevier
Traumatic brain injury (TBI) is a serious global health issue, being the leading cause of
death and disability for individuals under the age of 45, and one of the largest causes of …