Extrahepatic delivery

JK Nair, M Maier, V Jadhav, S Milstein… - US Patent …, 2024 - Google Patents
OVRNDRQMDRJTHS-CBQIKETKSA-N N-Acetyl-D-Galactosamine Chemical compound CC
(= O) N [C@ H] 1 [C@@ H](O) O [C@ H](CO)[C@ H](O)[C@@ H] 1O OVRNDRQMDRJTHS …

Chemically modified RNA aptamers and uses thereof

M Levy, A Bhowmick - US Patent 11,008,576, 2021 - Google Patents
Provided are chemically modified ribonucleic acid (RNA) aptamers comprising one or more
of 2'F guanylate, 2'OMe cytidylate, 2'OMe adenylate, and a deoxy pyrimidine nucleotide with …