The evolution and structure/function of bHLH–PAS transcription factor family

HE Edwards, DA Gorelick - Biochemical Society Transactions, 2022 - portlandpress.com
Proteins that contain basic helix-loop-helix (bHLH) and Per-Arnt-Sim motifs (PAS) function
as transcription factors. bHLH–PAS proteins exhibit essential and diverse functions …

Genome editing in chickens

K Ichikawa, M Matsuzaki, R Ezaki, H Horiuchi - Gene and Genome Editing, 2022 - Elsevier
Chicken (Gallus gallus) is a major protein source and an important model organism in the
avian species. Although genome editing has enabled genetic modifications of various …

Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2

K Mattonet, FW Riemslagh, S Guenther… - Science …, 2022 - science.org
Endothelial specification is a key event during embryogenesis; however, when, and how,
endothelial cells separate from other lineages is poorly understood. In zebrafish, Npas4l is …

ETV2 induces endothelial, but not hematopoietic, lineage specification in birds

W Weng, Y Deng, R Deviatiiarov… - Life Science …, 2024 - life-science-alliance.org
Cardiovascular system develops from the lateral plate mesoderm. Its three primary cell
lineages (hematopoietic, endothelial, and muscular) are specified by the sequential actions …

Hemato-vascular specification requires arnt1 and arnt2 genes in zebrafish embryos

HE Edwards, MJ Elizalde, JP Souder… - …, 2023 - journals.biologists.com
During embryonic development, a subset of cells in the mesoderm germ layer are specified
as hemato-vascular progenitor cells, which then differentiate into endothelial cells and …