Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Recent advances in Alzheimer's disease: Mechanisms, clinical trials and new drug development strategies
Alzheimer's disease (AD) stands as the predominant form of dementia, presenting significant
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …
The amyloid cascade hypothesis: an updated critical review
Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …
disease have created excitement and have been heralded as corroboration of the amyloid …
Lactylation of METTL16 promotes cuproptosis via m6A-modification on FDX1 mRNA in gastric cancer
L Sun, Y Zhang, B Yang, S Sun, P Zhang, Z Luo… - Nature …, 2023 - nature.com
Cuproptosis, caused by excessively high copper concentrations, is urgently exploited as a
potential cancer therapeutic. However, the mechanisms underlying the initiation …
potential cancer therapeutic. However, the mechanisms underlying the initiation …
Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical potential
L Gao, Y Zhang, K Sterling, W Song - Translational neurodegeneration, 2022 - Springer
Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …
arise as the disease progresses. A growing body of evidence suggests that pathological …
Cope with copper: From copper linked mechanisms to copper-based clinical cancer therapies
X Wang, M Zhou, Y Liu, Z Si - Cancer letters, 2023 - Elsevier
Recent studies have established a strong link between copper and cancer biology, as
copper is necessary for cancer growth and metastasis. Beyond the conventional concept of …
copper is necessary for cancer growth and metastasis. Beyond the conventional concept of …
Copper in tumors and the use of copper-based compounds in cancer treatment
Copper homeostasis is strictly regulated by protein transporters and chaperones, to allow its
correct distribution and avoid uncontrolled redox reactions. Several studies address copper …
correct distribution and avoid uncontrolled redox reactions. Several studies address copper …
Copper dyshomeostasis in neurodegenerative diseases—therapeutic implications
G Gromadzka, B Tarnacka, A Flaga… - International journal of …, 2020 - mdpi.com
Copper is one of the most abundant basic transition metals in the human body. It takes part
in oxygen metabolism, collagen synthesis, and skin pigmentation, maintaining the integrity …
in oxygen metabolism, collagen synthesis, and skin pigmentation, maintaining the integrity …
The important role of zinc in neurological diseases
Zinc is one of the most abundant metal ions in the central nervous system (CNS), where it
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …
[HTML][HTML] Common and trace metals in Alzheimer's and Parkinson's diseases
J Doroszkiewicz, JA Farhan, J Mroczko… - International journal of …, 2023 - mdpi.com
Trace elements and metals play critical roles in the normal functioning of the central nervous
system (CNS), and their dysregulation has been implicated in neurodegenerative disorders …
system (CNS), and their dysregulation has been implicated in neurodegenerative disorders …
Zinc and COVID-19: basis of current clinical trials
Abstract Coronavirus disease-2019 (COVID-19) pandemic continues to threaten patients,
societies, and economic and healthcare systems around the world. Like many other …
societies, and economic and healthcare systems around the world. Like many other …