Eosinophils are bone marrow-derived granulocytes that are traditionally associated with
type 2 immune responses, such as those that occur during parasite infections and allergy …

Eosinophils are typically considered tissue-damaging effector cells in type 2 immune-related
diseases. However, they are also increasingly recognized as important modulators of …

The intestine harbors a large population of resident eosinophils, yet the function of intestinal
eosinophils has not been explored. Flow cytometry and whole-mount imaging identified …

Type 2 cytokine responses promote parasitic immunity and initiate tissue repair; however,
they can also result in immunopathologies when not properly restricted. Although basophilia …

Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a
plethora of responses ranging from regulation of tissue homeostasis to host defense and …

Eosinophils (Eos) reside in multiple organs during homeostasis and respond rapidly to an
inflammatory challenge. Although Eos share chemical staining properties, they also …

Background Microbial colonization and immune cell maturation coincide at mucosal sites
and are decisive for postnatal lung development. How external factors influence neonatal …

Respiratory tract infections are a leading cause of morbidity and mortality in newborns,
infants, and young children. These early life infections present a formidable immunologic …

Pulmonary hypertension (PH) is a multifaceted condition characterized by elevated
pulmonary arterial pressure, which can result in right ventricular dysfunction and failure …

Background Pulmonary eosinophils comprise at least two distinct populations of resident
eosinophils (rEOS) and inflammatory eosinophils (iEOS), the latter recruited in response to …