Biosensing with dnazymes

EM McConnell, I Cozma, Q Mou, JD Brennan… - Chemical Society …, 2021 - pubs.rsc.org
This article provides a comprehensive review of biosensing with DNAzymes, providing an
overview of different sensing applications while highlighting major progress and seminal …

Metal sensing by DNA

W Zhou, R Saran, J Liu - Chemical reviews, 2017 - ACS Publications
Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …

Building machines with DNA molecules

H Ramezani, H Dietz - Nature Reviews Genetics, 2020 - nature.com
In nature, DNA molecules carry the hereditary information. But DNA has physical and
chemical properties that make it attractive for uses beyond heredity. In this Review, we …

Aptamer chemistry

P Röthlisberger, M Hollenstein - Advanced drug delivery reviews, 2018 - Elsevier
Aptamers are single-stranded DNA or RNA molecules capable of tightly binding to specific
targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution …

Catalytic DNA: scope, applications, and biochemistry of deoxyribozymes

SK Silverman - Trends in biochemical sciences, 2016 - cell.com
The discovery of natural RNA enzymes (ribozymes) prompted the pursuit of artificial DNA
enzymes (deoxyribozymes) by in vitro selection methods. A key motivation is the conceptual …

Chemistry can make strict and fuzzy controls for bio-systems: DNA nanoarchitectonics and cell-macromolecular nanoarchitectonics

M Komiyama, K Yoshimoto, M Sisido… - Bulletin of the Chemical …, 2017 - academic.oup.com
In this review, we introduce two kinds of bio-related nanoarchitectonics, DNA
nanoarchitectonics and cell-macromolecular nanoarchitectonics, both of which are basically …

Nucleic‐acid structures as intracellular probes for live cells

D Samanta, SB Ebrahimi, CA Mirkin - Advanced Materials, 2020 - Wiley Online Library
The chemical composition of cells at the molecular level determines their growth,
differentiation, structure, and function. Probing this composition is powerful because it …

Metal organic framework coated MnO2 nanosheets delivering doxorubicin and self-activated DNAzyme for chemo-gene combinatorial treatment of cancer

Y Nie, D Li, Y Peng, S Wang, S Hu, M Liu, J Ding… - International journal of …, 2020 - Elsevier
Abstract The RNA-cleaving DNAzyme (DZ) holds promising potential for RNA interference
(RNAi) applications and is favored over siRNA owing to its high chemical stability …

DNA‐based nanoarchitectures as eminent vehicles for smart drug delivery systems

M Komiyama, N Shigi, K Ariga - Advanced Functional Materials, 2022 - Wiley Online Library
In order to cure diseases efficiently with minimal side effects in sophisticated medicine,
eminent drugs must be selectively delivered to diseased parts and allow to work only there …

Programmable DNA switches and their applications

SG Harroun, C Prévost-Tremblay, D Lauzon… - Nanoscale, 2018 - pubs.rsc.org
DNA switches are ideally suited for numerous nanotechnological applications, and
increasing efforts are being directed toward their engineering. In this review, we discuss how …