Oxytocin (Oxt) is a nonapeptide hormone best known for its role in lactation and parturition.
Since 1906 when its uterine-contracting properties were described until 50 years later when …

Obesity and its associated complications have reached epidemic proportions in the USA
and also worldwide, highlighting the need for new and more effective treatments. Although …

Nesfatin-1 is a recently identified anorexigenic peptide derived from its precursor protein,
nonesterified fatty acid/nucleobindin 2 (NUCB2). Although the hypothalamus is pivotal for …

Hypothalamic nesfatin-1, derived from the nucleobindin2 (NUCB2) precursor, inhibits
nocturnal food intake and body weight gain in rats. Nesfatin-1 is able to cross the blood …

Nesfatin-1 is a novel satiety molecule in the hypothalamus and is also present in peripheral
tissues. Here we sought to identify the active segment of nesfatin-1 and to determine the …

The hypothalamic paraventricular nucleus (PVN) functions as a center to integrate various
neuronal activities for regulating feeding behavior. Nesfatin-1, a recently discovered …

Nesfatin-1, derived from nucleobindin2, is expressed in the hypothalamus and reported in
one study to reduce food intake (FI) in rats. To characterize the central anorexigenic action of …

The protein fragment nesfatin-1 was recently implicated in the control of food intake. Central
administration of this fragment results in anorexia and reduced body weight gain, whereas …

The novel satiety factor nesfatin-1 has been shown to decrease food intake and body weight
in rodents after icv injection. However, no further developments regarding the true patho …

Nesfatin-1 was discovered in 2006 and implicated in the regulation of food intake.
Subsequently, its widespread central and peripheral distribution gave rise to additional …