Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology: update 2017
C Hiemke, N Bergemann, HW Clement… - …, 2018 - thieme-connect.com
Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …
AGNP consensus guidelines for therapeutic drug monitoring in psychiatry: update 2011
Therapeutic drug monitoring (TDM), ie, the quantification of serum or plasma concentrations
of medications for dose optimization, has proven a valuable tool for the patient-matched …
of medications for dose optimization, has proven a valuable tool for the patient-matched …
Antipsychotic dose, dopamine D2 receptor occupancy and extrapyramidal side-effects: a systematic review and dose-response meta-analysis
Antipsychotic drugs differ in their propensity to cause extrapyramidal side-effects (EPS), but
their dose-effects are unclear. Therefore, we conducted a systematic review and dose …
their dose-effects are unclear. Therefore, we conducted a systematic review and dose …
Dopamine in drug abuse and addiction: results from imaging studies and treatment implications
The involvement of dopamine in drug reinforcement is well recognized but its role in drug
addiction is much less clear. Imaging studies have shown that the reinforcing effects of drugs …
addiction is much less clear. Imaging studies have shown that the reinforcing effects of drugs …
Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery
The worldwide market for therapies for CNS disorders is worth more than $50 billion and is
set to grow substantially in the years ahead. This is because: 1) the incidence of many CNS …
set to grow substantially in the years ahead. This is because: 1) the incidence of many CNS …
Dopaminergic modulation of limbic and cortical drive of nucleus accumbens in goal-directed behavior
Goal-directed behavior is believed to involve interactions of prefrontal cortical and limbic
inputs in the nucleus accumbens (NAcc), and their modulation by mesolimbic dopamine …
inputs in the nucleus accumbens (NAcc), and their modulation by mesolimbic dopamine …
Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia
Atypical antipsychotics have greatly enhanced the treatment of schizophrenia. The
mechanisms underlying the effectiveness and adverse effects of these drugs are, to date, not …
mechanisms underlying the effectiveness and adverse effects of these drugs are, to date, not …
Modern antipsychotic drugs: a critical overview
DM Gardner, RJ Baldessarini, P Waraich - Cmaj, 2005 - Can Med Assoc
CONVENTIONAL ANTIPSYCHOTIC DRUGS, used for a half century to treat a range of major
psychiatric disorders, are being replaced in clinical practice by modern “atypical” …
psychiatric disorders, are being replaced in clinical practice by modern “atypical” …
Endocrine and metabolic adverse effects of psychotropic medications in children and adolescents
CU Correll, HE Carlson - Journal of the American Academy of Child & …, 2006 - Elsevier
OBJECTIVE:: Despite increasing use of psychotropic medications in children and
adolescents, data regarding their efficacy and safety are limited. Endocrine and metabolic …
adolescents, data regarding their efficacy and safety are limited. Endocrine and metabolic …
Aripiprazole: a comprehensive review of its pharmacology, clinical efficacy, and tolerability
A DeLeon, NC Patel, ML Crismon - Clinical therapeutics, 2004 - Elsevier
Background: Recently approved for the treatment of schizophrenia, aripiprazole represents
the sixth second-generation antipsychotic (SGA) introduced to the US market. Aripiprazole is …
the sixth second-generation antipsychotic (SGA) introduced to the US market. Aripiprazole is …