[HTML][HTML] Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration

A Atwal, TP Dale, M Snow, NR Forsyth… - Advances in colloid and …, 2023‏ - Elsevier
The impairment of articular cartilage due to traumatic incidents or osteoarthritis has posed
significant challenges for healthcare practitioners, researchers, and individuals suffering …

Concentrated bone marrow aspirate for the treatment of chondral injuries and osteoarthritis of the knee: a systematic review of outcomes

J Chahla, CS Dean, G Moatshe… - … journal of sports …, 2016‏ - journals.sagepub.com
Background: Bone marrow aspirate concentrate (BMAC) has emerged as a novel treatment
for pathology of the knee. Despite containing a limited number of stem cells, BMAC serves …

The use of mesenchymal stem cells for cartilage repair and regeneration: a systematic review

A Goldberg, K Mitchell, J Soans, L Kim… - Journal of orthopaedic …, 2017‏ - Springer
Background The management of articular cartilage defects presents many clinical
challenges due to its avascular, aneural and alymphatic nature. Bone marrow stimulation …

One-stage cartilage repair using a hyaluronic acid–based scaffold with activated bone marrow–derived mesenchymal stem cells compared with microfracture: five …

A Gobbi, GP Whyte - The American journal of sports …, 2016‏ - journals.sagepub.com
Background: Articular cartilage injury is frequently encountered, yet treatment options
capable of providing durable cartilage repair are limited. Purpose: To investigate the …

Biomaterials and tissue engineering approaches using glycosaminoglycans for tissue repair: Lessons learned from the native extracellular matrix

R Menezes, R Vincent, L Osorno, P Hu, TL Arinzeh - Acta biomaterialia, 2023‏ - Elsevier
Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …

Long-term clinical outcomes of one-stage cartilage repair in the knee with hyaluronic acid–based scaffold embedded with mesenchymal stem cells sourced from bone …

A Gobbi, GP Whyte - The American journal of sports …, 2019‏ - journals.sagepub.com
Background: Cell-based cartilage repair performed as a single-stage procedure is an
important advancement in the treatment of full-thickness cartilage injury and has potential for …

[HTML][HTML] Bone marrow aspirate concentrate harvesting and processing technique

J Chahla, S Mannava, ME Cinque, AG Geeslin… - Arthroscopy …, 2017‏ - Elsevier
Bone marrow obtained by iliac crest aspiration is a common source for harvesting
mesenchymal stem cells, other progenitor cells, and associated cytokine/growth factors …

Chondral lesions of the knee: an evidence-based approach

TJ Dekker, ZS Aman, NN DePhillipo, JF Dickens… - JBJS, 2021‏ - journals.lww.com
JBJS JBJS Journal Case Connector Reviews JBJS.org Surgical Techniques Open Access JOPA
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Stem cells in articular cartilage regeneration

G Filardo, F Perdisa, A Roffi, M Marcacci… - Journal of orthopaedic …, 2016‏ - Springer
Abstract Background Mesenchymal stem cells (MSCs) have emerged as a promising option
to treat articular chondral defects and early OA stages. However, their potential and …

Characterization of growth factors, cytokines, and chemokines in bone marrow concentrate and platelet-rich plasma: a prospective analysis

CG Ziegler, R Van Sloun, S Gonzalez… - … American journal of …, 2019‏ - journals.sagepub.com
Background: Platelet-rich plasma (PRP) and bone marrow concentrate (BMC) are
orthobiologic therapies with numerous growth factors and other bioactive molecules. Before …