[HTML][HTML] Research on artificial-intelligence-assisted medicine: a survey on medical artificial intelligence

F Gou, J Liu, C **ao, J Wu - Diagnostics, 2024 - mdpi.com
With the improvement of economic conditions and the increase in living standards, people's
attention in regard to health is also continuously increasing. They are beginning to place …

From bench to bedside: cutting-edge applications of base editing and prime editing in precision medicine

W Xu, S Zhang, H Qin, K Yao - Journal of Translational Medicine, 2024 - Springer
CRISPR-based gene editing technology theoretically allows for precise manipulation of any
genetic target within living cells, achieving the desired sequence modifications. This …

TadA-Derived Cytosine Base Editor for Precise Genome Editing in Zebrafish

W Qin, SJ Lin, C Petree, P Varshney, GK Varshney - bioRxiv, 2025 - biorxiv.org
CRISPR base editors are crucial for precise genome manipulation. Existing APOBECbased
cytosine base editors (CBEs), while powerful, exhibit indels and sequence context …

Structural basis for sequence context-independent single-stranded DNA cytosine deamination by the bacterial toxin SsdA

L Yin, K Shi, Y Chen, RS Harris, H Aihara - bioRxiv, 2024 - biorxiv.org
DNA deaminase toxins are involved in interbacterial antagonism and the generation of
genetic diversity in surviving bacterial populations. These enzymes have also been adopted …

植物线粒体基因组编辑研究进展.

张硕, 阚俊虎, 周家伟, 武志** - Biotechnology Bulletin, 2024 - search.ebscohost.com
线粒体是真核生物细胞内的半自主细胞器, 具有自身的基因组(mtDNA), 在生命活动中扮演重要
角色. 人类mtDNA 突变与多种遗传疾病相关, 而在植物中mtDNA 高频重组产生的ORF …

[CITATION][C] AI empowers exploration of protein universe

W Wang, X Huang - Science China Life Sciences, 2025 - Springer
Deaminases which perform the function of converting cytosine to thymine are ubiquitous in
nature with over 120,000 known variants, each exhibiting significant differences. However …