Physical models of collective cell migration

R Alert, X Trepat - Annual Review of Condensed Matter Physics, 2020 - annualreviews.org
Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

[HTML][HTML] Plasticity of cancer cell invasion: Patterns and mechanisms

J Wu, J Jiang, B Chen, K Wang, Y Tang, X Liang - Translational oncology, 2021 - Elsevier
Cancer cell migration and invasion are integral components of metastatic disease, which is
the major cause of death in cancer patients. Cancer cells can disseminate and migrate via …

Mechanisms of neural crest migration

A Szabó, R Mayor - Annual Review of Genetics, 2018 - annualreviews.org
Neural crest cells are a transient embryonic cell population that migrate collectively to
various locations throughout the embryo to contribute a number of cell types to several …

Physical models of collective cell motility: from cell to tissue

BA Camley, WJ Rappel - Journal of physics D: Applied physics, 2017 - iopscience.iop.org
In this article, we review physics-based models of collective cell motility. We discuss a range
of techniques at different scales, ranging from models that represent cells as simple self …

Mechanisms and in vivo functions of contact inhibition of locomotion

B Stramer, R Mayor - Nature reviews Molecular cell biology, 2017 - nature.com
Contact inhibition of locomotion (CIL) is a process whereby a cell ceases motility or changes
its trajectory upon collision with another cell. CIL was initially characterized more than half a …

Rules of collective migration: from the wildebeest to the neural crest

A Shellard, R Mayor - Philosophical Transactions of the …, 2020 - royalsocietypublishing.org
Collective migration, the movement of groups in which individuals affect the behaviour of
one another, occurs at practically every scale, from bacteria up to whole species' …

Learning dynamical models of single and collective cell migration: a review

D Brückner, CP Broedersz - Reports on Progress in Physics, 2024 - iopscience.iop.org
Single and collective cell migration are fundamental processes critical for physiological
phenomena ranging from embryonic development and immune response to wound healing …

Cell migration: from tissue culture to embryos

G Reig, E Pulgar, ML Concha - Development, 2014 - journals.biologists.com
Cell migration is a fundamental process that occurs during embryo development. Classic
studies using in vitro culture systems have been instrumental in dissecting the principles of …

Polarity mechanisms such as contact inhibition of locomotion regulate persistent rotational motion of mammalian cells on micropatterns

BA Camley, Y Zhang, Y Zhao, B Li… - Proceedings of the …, 2014 - National Acad Sciences
Pairs of endothelial cells on adhesive micropatterns rotate persistently, but pairs of
fibroblasts do not; coherent rotation is present in normal mammary acini and kidney cells but …

Learning black-and gray-box chemotactic PDEs/closures from agent based Monte Carlo simulation data

S Lee, YM Psarellis, CI Siettos, IG Kevrekidis - Journal of Mathematical …, 2023 - Springer
We propose a machine learning framework for the data-driven discovery of macroscopic
chemotactic Partial Differential Equations (PDEs)—and the closures that lead to them-from …