Nuclear lamins are type V intermediate filament proteins that polymerize into complex
filamentous meshworks at the nuclear periphery and in less structured forms throughout the …

Nuclear lamins are type‐V intermediate filaments that are involved in many nuclear
processes. In mammals, A‐and B‐type lamins assemble into separate physical meshwork …

Diabetic wound healing (DWH) represents a major complication of diabetes where
inflammation is a key impediment to proper healing. The cyclic GMP-AMP synthase (cGAS) …

Assembly of macromolecular complexes at correct cellular sites is crucial for cell function.
Nuclear pore complexes (NPCs) are large cylindrical assemblies with eightfold rotational …

In mammalian cell nuclei, the nuclear lamina (NL) underlies the nuclear envelope (NE) to
maintain nuclear structure. The nuclear lamins, the major structural components of the NL …

The nuclear basket (NB) is an essential structure of the nuclear pore complex (NPC) and
serves as a dynamic and multifunctional platform that participates in various critical nuclear …

The ability of a cell to regulate its mechanical properties is central to its function. Emerging
evidence suggests that interactions between the cell nucleus and cytoskeleton influence cell …

The nuclear lamina serves important functions in the nucleus, providing structural support to
the nuclear envelope and contributing to chromatin organization. The primary proteins that …

The organization of eukaryotic genome in the nucleus, a double-membraned organelle
separated from the cytoplasm, is highly complex and dynamic. The functional architecture of …

Mutations in the genes LMNA and BANF1 can lead to accelerated aging syndromes called
progeria. The protein products of these genes, A-type lamins and BAF, respectively, are …