GnRH and its analogs are used extensively for the treatment of hormone-dependent
diseases and assisted reproductive techniques. They also have potential as novel …

GnRH is the pivotal hypothalamic hormone regulating reproduction. Over 20 forms of the
decapeptide have been identified in which the NH2-and COOH-terminal sequences, which …

Objective: To investigate the expression and function of GnRH and GnRH receptor (GnRHR)
subtypes at the maternal-fetal interface. Design: In vitro experiments using freshly isolated …

Fish have been of paramount importance to our understanding of vertebrate comparative
neuroendocrinology and the mechanisms underlying the physiology and evolution of …

The orphan nuclear hormone receptor SHP has been proposed to have a key role in the
negative feedback regulation of bile acid production. Consistent with this, mice lacking the …

The key component regulating vertebrate puberty and sexual maturation is the endocrine
system primarily effectuated along the brain–pituitary–gonad (BPG) axis. By far most …

In human beings, two forms of GnRH, termed GnRH-I and GnRH-II, encoded by separate
genes have been identified. Although these hormones share comparable cDNA and …

The neuropeptide gonadotropin‐releasing hormone (GnRH) has a central role in the neural
control of vertebrate reproduction. This review describes an overview of what is currently …

About 50years after Harris's first demonstration of its existence, GnRH has strongly
stimulated the interest and imagination of scientists, resulting in a high number of studies in …

Hypothalamic gonadotrophin-releasing hormone (GnRH I), which is of a variable structure in
vertebrates, is the central regulator of the reproductive system through its stimulation of …