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Recent advances in the catalytic asymmetric Friedel–Crafts reactions of indoles
Functionalized chiral indole derivatives are privileged and versatile organic frameworks
encountered in numerous pharmaceutically active agents and biologically active natural …
encountered in numerous pharmaceutically active agents and biologically active natural …
β-Carboline alkaloid monomers and dimers: Occurrence, structural diversity, and biological activities
J Dai, W Dan, U Schneider, J Wang - European Journal of Medicinal …, 2018 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with great
structural diversity and outstanding biological activities. This review covers critically …
structural diversity and outstanding biological activities. This review covers critically …
Metal-mediated and metal-catalyzed reactions under mechanochemical conditions
The extraordinary impact of metal-based complexes on synthetic methods is still recognized
nowadays, and attempts are currently undertaken to further extend the use of metal-assisted …
nowadays, and attempts are currently undertaken to further extend the use of metal-assisted …
Metamorphosis of cycloalkenes for the divergent total synthesis of polycyclic indole alkaloids
Z Xu, Q Wang, J Zhu - Chemical Society Reviews, 2018 - pubs.rsc.org
From tryptamine and secologanine, nature generates monoterpene indole alkaloids with an
unprecedented level of skeletal diversity through a 'couple–divert'sequence. Intrigued by this …
unprecedented level of skeletal diversity through a 'couple–divert'sequence. Intrigued by this …
Palladium-Catalyzed Asymmetric Allylic Alkylation of 3-Substituted 1H-Indoles and Tryptophan Derivatives with Vinylcyclopropanes
BM Trost, WJ Bai, C Hohn, Y Bai… - Journal of the American …, 2018 - ACS Publications
Vinylcyclopropanes (VCPs) are known to generate 1, 3-dipoles with a palladium catalyst that
initially serve as nucleophiles to undergo [3+ 2] cycloadditions with electron-deficient olefins …
initially serve as nucleophiles to undergo [3+ 2] cycloadditions with electron-deficient olefins …
Pharmaceutical prospects of naturally occurring quinazolinone and its derivatives
D He, M Wang, S Zhao, Y Shu, H Zeng, C **ao, C Lu… - Fitoterapia, 2017 - Elsevier
Quinazolinones belong to a family of heterocyclic nitrogen compounds that have attracted
increasing interest because of their broad spectrum of biological functions. This review …
increasing interest because of their broad spectrum of biological functions. This review …
Hypoiodite-catalyzed oxidative umpolung of indoles for enantioselective dearomatization
H Tanaka, N Ukegawa, M Uyanik… - Journal of the American …, 2022 - ACS Publications
Here we report the oxidative umpolung of 2, 3-disubstituted indoles toward enantioselective
dearomative aza-spirocyclization to give the corresponding spiroindolenines using chiral …
dearomative aza-spirocyclization to give the corresponding spiroindolenines using chiral …
Development of a general and selective nanostructured cobalt catalyst for the hydrogenation of benzofurans, indoles and benzothiophenes
The selective hydrogenation of benzofurans in the presence of a heterogeneous non‐noble
metal catalyst is reported. The developed optimal catalytic material consists of cobalt‐cobalt …
metal catalyst is reported. The developed optimal catalytic material consists of cobalt‐cobalt …
Synthetic approaches to tetracyclic indolines as versatile building blocks of diverse indole Alkaloids
Y Wang, F **e, B Lin, M Cheng… - Chemistry–A European …, 2018 - Wiley Online Library
Indole alkaloids bearing the tetracyclic indoline scaffolds of 1H‐pyrrolo [2, 3‐d] carbazole
have shown fascinating chemical diversity and significant biological activities. The …
have shown fascinating chemical diversity and significant biological activities. The …
Total synthesis of the pseudoindoxyl class of natural products
The pseudoindoxyl sub-structural motif, amongst the large set of the indole class of
alkaloids, represents a unique subset of the oxygenated indole class of the alkaloid family. A …
alkaloids, represents a unique subset of the oxygenated indole class of the alkaloid family. A …