This guideline presents recommendations for the management of patients with hereditary
gastrointestinal cancer syndromes. The initial assessment is the collection of a family history …

Serrated lesions of the colorectum are the precursors of perhaps one-third of colorectal
cancers (CRCs). Cancers arising in serrated lesions are usually in the proximal colon, and …

ESGE recommends that individuals with hereditary gastrointestinal polyposis syndromes
should be surveilled in dedicated units that provide monitoring of compliance and …

This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy
(ESGE). The Grading of Recommendations Assessment, Development, and Evaluation …

Between 2% to 5% of all colon cancers arise in the setting of well-defined inherited
syndromes, including Lynch syndrome, familial adenomatous polyposis, MUTYH-associated …

The “serrated neoplastic pathway” describes the progression of serrated polyps, including
sessile serrated adenomas and traditional serrated adenomas, to colorectal cancer. The …

The present article summarizes recent developments in the characterization of genetic
predisposition to colorectal cancer (CRC). The main themes covered include new hereditary …

Colorectal cancer (CRC) is the fourth most common cancer amongst men and women.
Between 3 and 6% of all CRCs are attributed to well-defined inherited syndromes, including …

Base excision repair is the system used from bacteria to man to remove the tens of
thousands of endogenous DNA damages produced daily in each human cell. Base excision …

Colorectal cancer (CRC) ranks among the three most common cancers in terms of both
cancer incidence and cancer‐related deaths in most Western countries. Serrated …