The ultimate goal of radiation oncology is to eradicate tumours without toxicity to non-
malignant tissues. FLASH radiotherapy, or the delivery of ultra-high dose rates of radiation …

Radiation-induced lymphopenia (RIL) is characterized by a significant decrease in the
absolute number of lymphocytes circulating in the blood after radiotherapy. With the major …

Purpose To explore the association of the effective dose to immune cells (EDIC) with
disease control, lymphopenia, and toxicity in patients with non-small cell lung cancer …

Voxel-based analysis (VBA) allows the full, 3-dimensional, dose distribution to be
considered in radiotherapy outcome analysis. This provides new insights into anatomical …

Immunotherapeutic agents have revolutionized cancer treatment over the past decade.
However, most patients fail to respond to immunotherapy alone. A growing body of …

Background/purpose Higher estimated radiation doses to immune cells (EDIC) have
correlated with worse overall survival (OS) in patients with locally-advanced non-small cell …

Radiation-induced lymphopenia (RIL) is a frequent, and often considered unavoidable, side
effect of radiation therapy (RT), whether or not chemotherapy is included. However, in the …

Purpose Radiation-induced lymphopenia has gained attention recently as the result of its
correlation with survival in a range of indications, particularly when combining radiation …

Simple Summary Radiation-induced esophagitis (RE) is a common dose-limiting
complication associated with concurrent chemoradiation therapy for Non-Small-Cell Lung …

Background Limited studies explored the relationship between lymphocyte recovery after
definitive concurrent chemoradiotherapy (dCCRT) and prognosis in esophageal squamous …