Aging of skin is an intricate biological process consisting of two types. While intrinsic or
chronological aging is an inevitable process, photoaging involves the premature aging of …

Intrinsic (chronological) skin ageing is characterized hy atrophy of the skin with loss of
elasticity and slowed metabolic activity. The superposition of environmental damage …

Background Bakuchiol is a phytochemical that has demonstrated cutaneous antiageing
effects when applied topically. Early studies have suggested that bakuchiol is a functional …

Background Topical tretinoin (retinoic acid) modifies fine wrinkles and certain other features
of human skin damaged by exposure to the sun (photodamage), but histologic changes do …

† Background and Design.—The assessment of the severity of cutaneous photodamage and
its response to treatment is an impractical consideration for most practitioners without …

• The clinical and histologic effects of a new emollient cream formulation of topical tretinoin
at concentrations of 0.05% and 0.01% were examined in 251 subjects with mild to moderate …

Thin skin and the appearance of bruises, seemingly unprovoked, are frequent complaints of
elderly patients. Chronic cutaneous insufficiencies such as these are termed …

Human skin exhibits a characteristic, pleiotypic response to topical retinoic acid. In
attempting to understand this response at the molecular level, we have used fast protein …

Advancements in understanding skin aging mechanisms, which encompass both external
and internal aging processes, have spurred the development of innovative treatments …

Background: Tretinoin administered topically in 0.1% concentration has been shown to
improve the wrinkling and irregular pigmentation of photoaged skin. Objective: The purpose …