Aetiology, genetics and prevention of secondary neoplasms in adult cancer survivors
LB Travis, WD Wahnefried, JM Allan… - Nature reviews Clinical …, 2013 - nature.com
Second and higher-order malignancies now comprise about 18% of all incident cancers in
the USA, superseding first primary cancers of the breast, lung, and prostate. The occurrence …
the USA, superseding first primary cancers of the breast, lung, and prostate. The occurrence …
Late effects of radiation therapy in pediatric patients and survivorship
Advances in multimodality therapy have led to childhood cancer cure rates over 80%.
However, surgery, chemotherapy, and radiotherapy may lead to debilitating or even fatal …
However, surgery, chemotherapy, and radiotherapy may lead to debilitating or even fatal …
Dosimetric comparison of five different techniques for craniospinal irradiation across 15 European centers: analysis on behalf of the SIOP-E-BTG (radiotherapy …
E Seravalli, M Bosman, Y Lassen-Ramshad… - Acta …, 2018 - Taylor & Francis
Abstract Purpose Conventional techniques (3D-CRT) for craniospinal irradiation (CSI) are
still widely used. Modern techniques (IMRT, VMAT, TomoTherapy®, proton pencil beam …
still widely used. Modern techniques (IMRT, VMAT, TomoTherapy®, proton pencil beam …
Medulloblastoma: from molecular subgroups to molecular targeted therapies
Brain tumors are the leading cause of cancer-related death in children, and
medulloblastoma (MB) is the most common malignant pediatric brain tumor. Advances in …
medulloblastoma (MB) is the most common malignant pediatric brain tumor. Advances in …
Therapeutic radiation and the potential risk of second malignancies
SC Kamran, A Berrington de Gonzalez, A Ng… - Cancer, 2016 - Wiley Online Library
Radiation has long been associated with carcinogenesis. Nevertheless, it is an important
part of multimodality therapy for many malignancies. It is critical to assess the risk of …
part of multimodality therapy for many malignancies. It is critical to assess the risk of …
Factors influencing risk‐based care of the childhood cancer survivor in the 21st century
SB Dixon, KL Bjornard, NM Alberts… - CA: a cancer journal …, 2018 - Wiley Online Library
The population of adult survivors of childhood cancer continues to grow as survival rates
improve. Although it is well established that these survivors experience various …
improve. Although it is well established that these survivors experience various …
Clinical commissioning of intensity‐modulated proton therapy systems: report of AAPM Task Group 185
Proton therapy is an expanding radiotherapy modality in the United States and worldwide.
With the number of proton therapy centers treating patients increasing, so does the need for …
With the number of proton therapy centers treating patients increasing, so does the need for …
Second tumor risk in children treated with proton therapy
Background Out‐of‐field neutron dissemination during double‐scattered proton therapy has
raised concerns of increased second malignancies, disproportionally affecting pediatric …
raised concerns of increased second malignancies, disproportionally affecting pediatric …
A comparative study on the risks of radiogenic second cancers and cardiac mortality in a set of pediatric medulloblastoma patients treated with photon or proton …
Purpose To compare the risks of radiogenic second cancers and cardiac mortality in 17
pediatric medulloblastoma patients treated with passively scattered proton or field-in-field …
pediatric medulloblastoma patients treated with passively scattered proton or field-in-field …
Craniospinal irradiation as part of re-irradiation for children with recurrent intracranial ependymoma
Background The goal of this study was to evaluate outcomes in children with relapsed,
molecularly characterized intracranial ependymoma treated with or without craniospinal …
molecularly characterized intracranial ependymoma treated with or without craniospinal …