The microRNA-29 family: role in metabolism and metabolic disease
The microRNA-29 family members miR-29a-3p, miR-29b-3p, and miR-29c-3p are
ubiquitously expressed and consistently increased in various tissues and cell types in …
ubiquitously expressed and consistently increased in various tissues and cell types in …
An update in epigenetics in metabolic-associated fatty liver disease
JS Rodríguez-Sanabria, R Escutia-Gutiérrez… - Frontiers in …, 2022 - frontiersin.org
Metabolic-associated fatty liver disease (MAFLD) is characterized by hepatic steatosis
accompanied by one of three features: overweight or obesity, T2DM, or lean or normal …
accompanied by one of three features: overweight or obesity, T2DM, or lean or normal …
[HTML][HTML] Neuronal miR-29a protects from obesity in adult mice
Y Ma, N Murgia, Y Liu, Z Li, C Sirakawin… - Molecular …, 2022 - Elsevier
Objective Obesity, a growing threat to the modern society, represents an imbalance of
metabolic queues that normally signal to the arcuate hypothalamic nucleus, a critical brain …
metabolic queues that normally signal to the arcuate hypothalamic nucleus, a critical brain …
Hepatocyte expression of the micropeptide adropin regulates the liver fasting response and is enhanced by caloric restriction
The micropeptide adropin encoded by the clock-controlled energy homeostasis–associated
gene is implicated in the regulation of glucose metabolism. However, its links to rhythms of …
gene is implicated in the regulation of glucose metabolism. However, its links to rhythms of …
Maternal fructose intake predisposes rat offspring to metabolic disorders via abnormal hepatic programming
Given that fructose consumption has increased by more than 10‐fold in recent decades, it is
possible that excess maternal fructose consumption causes harmful effects in the next …
possible that excess maternal fructose consumption causes harmful effects in the next …
Role of micro‐RNAs associated with adipose‐derived extracellular vesicles in metabolic disorders
T Payet, E Gabinaud, JF Landrier… - Obesity Reviews, 2024 - Wiley Online Library
Micro‐RNAs have emerged as important actors in the onset of metabolic disorders including
obesity or type 2 diabetes. Particularly, several micro‐RNAs are known to be key modulators …
obesity or type 2 diabetes. Particularly, several micro‐RNAs are known to be key modulators …
miR-29 is an important driver of aging-related phenotypes
Aging is a consequence of complex molecular changes, but whether a single microRNA
(miRNA) can drive aging remains unclear. A miRNA known to be upregulated during both …
(miRNA) can drive aging remains unclear. A miRNA known to be upregulated during both …
Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health
Preterm birth (PTB) is associated with increased risk of type 2 diabetes and neurocognitive
impairment later in life. We analyzed for the first time the associations of PTB with blood …
impairment later in life. We analyzed for the first time the associations of PTB with blood …
Potential mechanisms of gut-derived extracellular vesicle participation in glucose and lipid homeostasis
T Feng, W Zhang, Z Li - Genes, 2022 - mdpi.com
The intestine participates in the regulation of glucose and lipid metabolism in multiple facets.
It is the major site of nutrient digestion and absorption, provides the interface as well as …
It is the major site of nutrient digestion and absorption, provides the interface as well as …
Signal transduction and molecular regulation in fatty liver disease
Significance: Fatty liver disease is a major liver disorder in the modern societies.
Comprehensive understanding of the pathophysiology and molecular mechanisms is …
Comprehensive understanding of the pathophysiology and molecular mechanisms is …