Cardiovascular diseases are the leading cause of global deaths, and many risk factors
contribute to their pathogenesis. In this context, prostanoids, which derive from arachidonic …

There is currently no medical therapy to prevent calcific aortic valve stenosis (CAVS). Multi-
omics approaches could lead to the identification of novel molecular targets. Here, we …

Our understanding of atrial fibrillation genetics is rapidly improving with larger and more
diverse genome-wide association studies. Translating genetic discoveries into molecular …

To broaden our understanding of bradyarrhythmias and conduction disease, we performed
common variant genome-wide association analyses in up to 1.3 million individuals and rare …

BACKGROUND: Subtle, prognostically important ECG features may not be apparent to
physicians. In the course of supervised machine learning, thousands of ECG features are …

The largemouth bass is a native species of North America that was first introduced to
mainland China in the 1980s. In recent years, it has been extensively farmed in China due to …

Observational studies have revealed that ischemic heart disease (IHD) has a unique
manifestation on electrocardiographic (ECG). However, the genetic relationships between …

Age is a prominent risk factor for cardiometabolic disease, often leading to heart structural
and functional changes. However, precise molecular mechanisms underlying cardiac …

Background Long‐QT syndrome (LQTS) is a cardiac repolarization abnormality that can
lead to sudden cardiac death. The most common causes are rare coding variants in the …

Abstract The 3-dimensional spatial and 2-dimensional frontal QRS-T angles are measures
derived from the vectorcardiogram. They are independent risk predictors for arrhythmia, but …