Heterogeneity and plasticity of epithelial–mesenchymal transition (EMT) in cancer metastasis: Focusing on partial EMT and regulatory mechanisms

D Li, L **a, P Huang, Z Wang, Q Guo, C Huang… - Cell …, 2023 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) or mesenchymal–epithelial transition (MET) plays
critical roles in cancer metastasis. Recent studies, especially those based on single‐cell …

Circulating tumor cells: from new biological insights to clinical practice

X Gu, S Wei, X Lv - Signal transduction and targeted therapy, 2024 - nature.com
The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …

Vimentin: Regulation and pathogenesis

D Paulin, A Lilienbaum, S Kardjian, O Agbulut, Z Li - Biochimie, 2022 - Elsevier
Vimentin, an abundant cytoplasmic intermediate filament protein, is recognized for its
important role in stabilizing intracellular structure. Vimentin has been recognized for its …

Green synthesis of zinc oxide nanoparticles using Rhus coriaria extract and their anticancer activity against triple-negative breast cancer cells

Y Mongy, T Shalaby - Scientific Reports, 2024 - nature.com
The growing interest in using plant extracts for the biogenic synthesis of zinc oxide
nanoparticles (ZnO NPs) stems from their facile, eco-friendly, and biologically safe approach …

Cancer-associated fibroblasts: Vital suppressors of the immune response in the tumor microenvironment

X **ang, YR Niu, ZH Wang, LL Ye, WB Peng… - Cytokine & Growth Factor …, 2022 - Elsevier
Since the" seed and soil" hypothesis was proposed, the biological functions of the tumor
microenvironment (TME), especially its stromal components, have received increasing …

Vimentin at the core of wound healing

LS Coelho-Rato, S Parvanian, MK Modi… - Trends in Cell Biology, 2024 - cell.com
As a member of the large family of intermediate filaments (IFs), vimentin has emerged as a
highly dynamic and versatile cytoskeletal protein involved in many key processes of wound …

[HTML][HTML] Do PFCAs drive the establishment of thyroid cancer microenvironment? Effects of C6O4, PFOA and PFHxA exposure in two models of human thyroid cells in …

F Coperchini, A Greco, L Croce, M Teliti, B Calì… - Environment …, 2024 - Elsevier
Background Exposure to environmental pollutants is suspected to be one of the potential
causes accounting for the increase in thyroid cancer (TC) incidence worldwide. Among the …

The effects of epithelial–mesenchymal transitions in COPD induced by cigarette smoke: an update

X Su, W Wu, Z Zhu, X Lin, Y Zeng - Respiratory research, 2022 - Springer
Cigarette smoke is a complex aerosol containing a large number of compounds with a
variety of toxicity and carcinogenicity. Long-term exposure to cigarette smoke significantly …

Targeting vimentin: a multifaceted approach to combatting cancer metastasis and drug resistance

A Tabatabaee, B Nafari, A Farhang, A Hariri… - Cancer and Metastasis …, 2024 - Springer
This comprehensive review explores vimentin as a pivotal therapeutic target in cancer
treatment, with a primary focus on mitigating metastasis and overcoming drug resistance …

Exploring new frontiers: cell surface vimentin as an emerging marker for circulating tumor cells and a promising therapeutic target in advanced gastric Cancer

H Li, YZ Zhu, L Xu, T Han, J Luan, X Li, Y Liu… - Journal of Experimental …, 2024 - Springer
Abstract Background Circulating tumor cells (CTCs) hold immense promise in guiding
treatment strategies for advanced gastric cancer (GC). However, their clinical impact has …