Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
Mucosal applications of poloxamer 407-based hydrogels: An overview
Poloxamer 407, also known by the trademark Pluronic® F127, is a water-soluble, non-ionic
triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) …
triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) …
Polymeric micelles as drug delivery vehicles
Though much progress has been made in drug delivery systems, the design of a suitable
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …
Micelles structure development as a strategy to improve smart cancer therapy
Micelles as colloidal suspension have attracted considerable attention due to their potential
use for both cancer diagnosis and therapy. These structures have proven their ability to …
use for both cancer diagnosis and therapy. These structures have proven their ability to …
Biomedical applications of biodegradable polymers
Utilization of polymers as biomaterials has greatly impacted the advancement of modern
medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant …
medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant …
Polymeric nanostructured materials for biomedical applications
Polymeric nanostructured materials (PNMs), which are polymeric materials in nanoscale or
polymer composites containing nanomaterials, have become increasingly useful for …
polymer composites containing nanomaterials, have become increasingly useful for …
Nanogels as pharmaceutical carriers: finite networks of infinite capabilities
AV Kabanov, SV Vinogradov - … Chemie International Edition, 2009 - Wiley Online Library
Nanogels are swollen nanosized networks composed of hydrophilic or amphiphilic polymer
chains. They are developed as carriers for the transport of drugs, and can be designed to …
chains. They are developed as carriers for the transport of drugs, and can be designed to …
Micellar nanocarriers: pharmaceutical perspectives
VP Torchilin - Pharmaceutical research, 2007 - Springer
Micelles, self-assembling nanosized colloidal particles with a hydrophobic core and
hydrophilic shell are currently successfully used as pharmaceutical carriers for water …
hydrophilic shell are currently successfully used as pharmaceutical carriers for water …
Structure and design of polymeric surfactant-based drug delivery systems
VP Torchilin - Journal of controlled release, 2001 - Elsevier
The review concentrates on the use of polymeric micelles as pharmaceutical carriers.
Micellization of biologically active substances is a general phenomenon that increases the …
Micellization of biologically active substances is a general phenomenon that increases the …
Poloxamer 188 as surfactant in biological formulations–An alternative for polysorbate 20/80?
L Bollenbach, J Buske, K Mäder, P Garidel - International Journal of …, 2022 - Elsevier
Surfactants are used to stabilize biologics. Particularly, polysorbates (Tween® 20 and
Tween® 80) dominate the group of surfactants in protein and especially antibody drug …
Tween® 80) dominate the group of surfactants in protein and especially antibody drug …