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Recent progress of solid lipid nanoparticles and nanostructured lipid carriers as ocular drug delivery platforms
Sufficient ocular bioavailability is often considered a challenge by the researchers, due to
the complex structure of the eye and its protective physiological mechanisms. In addition, the …
the complex structure of the eye and its protective physiological mechanisms. In addition, the …
Formulation of hesperidin‐loaded in situ gel for ocular drug delivery: a comprehensive study
BACKGROUND Allergic conjunctivitis is one of the most common eye disorders. Different
drugs are used for its treatment. Hesperidin is an active substance isolated from Citrus …
drugs are used for its treatment. Hesperidin is an active substance isolated from Citrus …
A comparative study between nanostructured lipid carriers and invasomes for the topical delivery of luteolin: design, optimization and pre-clinical investigations for …
M El-Kayal, S Hatem - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Psoriasis is an inflammatory skin condition manifested by hyper-proliferation and reactive
aberrant epidermal differentiation, in which genetic and environmental factors have a …
aberrant epidermal differentiation, in which genetic and environmental factors have a …
[HTML][HTML] Development of ciprofloxacin-loaded bilosomes in-situ gel for ocular delivery: optimization, in-vitro characterization, ex-vivo permeation, and antimicrobial …
Conventional eye drops are most commonly employed topically in the eye for the
management of bacterial conjunctivitis. Eye drops have a low corneal residence time and 90 …
management of bacterial conjunctivitis. Eye drops have a low corneal residence time and 90 …
[HTML][HTML] Novel anti-psoriatic nanostructured lipid carriers for the cutaneous delivery of luteolin: A comprehensive in-vitro and in-vivo evaluation
S Hatem, M El-Kayal - European Journal of Pharmaceutical Sciences, 2023 - Elsevier
Psoriasis is a prevalent laborious inflammation in skin with alternate phases of remission
and relapses. The current study sought to develop nanostructured lipid carriers (NLCs) …
and relapses. The current study sought to develop nanostructured lipid carriers (NLCs) …
Harnessing silk fibroin microparticles for metformin delivery: A novel approach to treating corneal neovascularization
Corneal neovascularization (CV) poses significant challenges in ophthalmology, often
leading to impaired vision and discomfort. Silk fibroin microparticles have emerged as …
leading to impaired vision and discomfort. Silk fibroin microparticles have emerged as …
Formulation development of Lornoxicam loaded heat triggered ocular in-situ gel using factorial design
Objective In the current research, lornoxicam-loaded in situ gels were developed, and their
potential usage in ocular inflammation was evaluated. Significance Lornoxicam cyclodextrin …
potential usage in ocular inflammation was evaluated. Significance Lornoxicam cyclodextrin …
[HTML][HTML] Besifloxacin nanocrystal: towards an innovative ophthalmic preparation
Bacterial conjunctivitis significantly impacts public health, including more than one-third of
eye diseases reported worldwide. It is an infection caused by various aerobic and anaerobic …
eye diseases reported worldwide. It is an infection caused by various aerobic and anaerobic …
Formulation Development of Dual Drug-Loaded Thermosensitive Ocular In Situ Gel Using Factorial Design
Purpose To overcome the problems of low bioavailability of the drug associated with the
short pre-corneal residence time, a thermoresponsive in situ gel system containing …
short pre-corneal residence time, a thermoresponsive in situ gel system containing …
Thermosensitive in situ gelling system for dermal drug delivery of rutin
Objectives: Rutin has been broadly applied for treating several diseases due to its
pharmacological activities. However, its low aqueous solubility limits its absorption and …
pharmacological activities. However, its low aqueous solubility limits its absorption and …