[PDF][PDF] Going around the Kok cycle of the water oxidation reaction with femtosecond X-ray crystallography

A Bhowmick, PS Simon, I Bogacz, R Hussein, M Zhang… - IUCrJ, 2023 - journals.iucr.org
The water oxidation reaction in photosystem II (PS II) produces most of the molecular oxygen
in the atmosphere, which sustains life on Earth, and in this process releases four electrons …

[PDF][PDF] Kilohertz serial crystallography with the JUNGFRAU detector at a fourth-generation synchrotron source

F Leonarski, J Nan, Z Matej, Q Bertrand, A Furrer… - IUCrJ, 2023 - journals.iucr.org
Serial and time-resolved macromolecular crystallography are on the rise. However, beam
time at X-ray free-electron lasers is limited and most third-generation synchrotron-based …

[PDF][PDF] 3D printed devices and infrastructure for liquid sample delivery at the European XFEL

M Vakili, J Bielecki, J Knoška, F Otte… - Journal of …, 2022 - journals.iucr.org
The Sample Environment and Characterization (SEC) group of the European X-ray Free-
Electron Laser (EuXFEL) develops sample delivery systems for the various scientific …

Photoswitch dissociation from a G protein-coupled receptor resolved by time-resolved serial crystallography

H Glover, T Saßmannshausen, Q Bertrand… - Nature …, 2024 - nature.com
G protein-coupled receptors (GPCRs) are the largest family of cell surface receptors in
humans. The binding and dissociation of ligands tunes the inherent conformational flexibility …

Fixed Target Serial Data Collection at Diamond Light Source.

S Horrell, D Axford, NE Devenish… - Journal of …, 2021 - repository.essex.ac.uk
Fixed Target Serial Data Collection at Diamond Light Source Page 1 Copyright © 2021 JoVE
Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License jove.com …

[PDF][PDF] Anaerobic fixed-target serial crystallography using sandwiched silicon nitride membranes

M Bjelčić, KGV Sigfridsson Clauss… - … Section D: Structural …, 2023 - journals.iucr.org
In recent years, the emergence of serial crystallography, initially pioneered at X-ray free-
electron lasers (XFELs), has sparked a growing interest in collecting macromolecular …

[HTML][HTML] Exploring serial crystallography for drug discovery

A Dunge, C Phan, O Uwangue, M Bjelcic… - IUCrJ, 2024 - journals.iucr.org
Structure-based drug design is highly dependent on the availability of structures of the
protein of interest in complex with lead compounds. Ideally, this information can be used to …

FragMAX Facility for Crystallographic Fragment and Ligand Screening at MAX IV

S Kanchugal P, E Jagudin, GMA Lima… - Applied …, 2025 - Wiley Online Library
The FragMAX facility at MAX IV Laboratory is a state‐of‐the‐art platform for crystallographic
fragment screening, designed to support structure‐based drug and chemical tool compound …

[HTML][HTML] Focused and coherent X-ray beams for advanced microscopies

D Carbone, O Bikondoa - Nuclear Instruments and Methods in Physics …, 2023 - Elsevier
The use of focused X-ray beams in the micron and sub-micron range has fostered the
progress of a wide range of scanning microscopy approaches that exploit the numerous …

Photochemical affinity switches to resolve ligand dissociation from a G protein-coupled receptor by time-resolved serial crystallography

J Standfuss, H Glover, T Sassmannshausen… - 2024 - researchsquare.com
G protein-coupled receptors (GPCRs) are the largest family of cell surface receptors in
humans. The binding and dissociation of ligands tunes the inherent conformational flexibility …