The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

Functioning as the exterior interface of the human body with the environment, skin acts as a
physical barrier to prevent the invasion of foreign pathogens while providing a home to the …

Human skin functions as a physical barrier to foreign pathogen invasion and houses
numerous commensals. Shifts in the human skin microbiome have been associated with …

The skin microbial community is a multifunctional ecosystem aiding prevention of infections
from transient pathogens, maintenance of host immune homeostasis, and skin health. A …

The importance of the microbiome to human health is increasingly recognized and has
become a major focus of recent research. However, much of the work has focused on a few …

The mycobiome is the fungal component of the human microbial ecosystem that represents
only a small part of this environment but plays an essential role in maintaining homeostasis …

Dysbiosis of the skin microbiota is increasingly implicated as a contributor to the
pathogenesis of atopic dermatitis (AD). We previously reported first-in-human safety and …

Fungal disease is an increasingly recognised global clinical challenge associated with high
mortality. Early diagnosis of fungal infection remains problematic due to the poor sensitivity …

Highlights•Malassezia are dominant eukaryotic microflora of human and animal
skin.•Malassezia interact with the mammalian host in both direct (toxic/irritant) and indirect …

Under steady-state conditions, the immune system is poised to sense and respond to the
microbiota. As such, immunity to the microbiota, including T cell responses, is expected to …