Chromatin and transcription in yeast
Understanding the mechanisms by which chromatin structure controls eukaryotic
transcription has been an intense area of investigation for the past 25 years. Many of the key …
transcription has been an intense area of investigation for the past 25 years. Many of the key …
Sin3: master scaffold and transcriptional corepressor
Sin3 was isolated over two decades ago as a negative regulator of transcription in budding
yeast. Subsequent research has established the protein as a master transcriptional scaffold …
yeast. Subsequent research has established the protein as a master transcriptional scaffold …
Arabidopsis WRKY38 and WRKY62 Transcription Factors Interact with Histone Deacetylase 19 in Basal Defense
KC Kim, Z Lai, B Fan, Z Chen - The Plant Cell, 2008 - academic.oup.com
Arabidopsis thaliana WRKY38 and WRKY62, encoding two structurally similar type III WRKY
transcription factors, are induced in a Nonexpressor of PR Gene1 (NPR1)–dependent …
transcription factors, are induced in a Nonexpressor of PR Gene1 (NPR1)–dependent …
Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress
Relocalization of proteins is a hallmark of the DNA damage response. We use high-
throughput microscopic screening of the yeast GFP fusion collection to develop a systems …
throughput microscopic screening of the yeast GFP fusion collection to develop a systems …
SirT1 regulation of antioxidant genes is dependent on the formation of a FoxO3a/PGC-1α complex
Y Olmos, FJ Sánchez-Gómez, B Wild… - Antioxidants & redox …, 2013 - liebertpub.com
SirT1 is a class III histone deacetylase that has been implicated in metabolic and reactive
oxygen species control. In the vasculature it has been shown to decrease endothelial …
oxygen species control. In the vasculature it has been shown to decrease endothelial …
Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation
Dynamic histone H3K4 methylation is an important epigenetic component of transcriptional
regulation. However, most of our current understanding of this histone mark is confined to …
regulation. However, most of our current understanding of this histone mark is confined to …
SIRT1 regulates the function of the Nijmegen breakage syndrome protein
Summary MRE11-RAD50-NBS1 (MRN) is a conserved nuclease complex that exhibits
properties of a DNA damage sensor and is critical in regulating cellular responses to DNA …
properties of a DNA damage sensor and is critical in regulating cellular responses to DNA …
Phosphorylated Pol II CTD recruits multiple HDACs, including Rpd3C (S), for methylation-dependent deacetylation of ORF nucleosomes
CK Govind, H Qiu, DS Ginsburg, C Ruan, K Hofmeyer… - Molecular cell, 2010 - cell.com
Methylation of histone H3 by Set1 and Set2 is required for deacetylation of nucleosomes in
coding regions by histone deacetylase complexes (HDACs) Set3C and Rpd3C (S) …
coding regions by histone deacetylase complexes (HDACs) Set3C and Rpd3C (S) …
Hyphal Development in Candida albicans Requires Two Temporally Linked Changes in Promoter Chromatin for Initiation and Maintenance
Y Lu, C Su, A Wang, H Liu - PLoS biology, 2011 - journals.plos.org
Phenotypic plasticity is common in development. For Candida albicans, the most common
cause of invasive fungal infections in humans, morphological plasticity is its defining feature …
cause of invasive fungal infections in humans, morphological plasticity is its defining feature …
The multifunctional Ccr4–Not complex directly promotes transcription elongation
The Ccr4–Not complex has been implicated in the control of multiple steps of mRNA
metabolism; however, its functions in transcription remain ambiguous. The discovery that …
metabolism; however, its functions in transcription remain ambiguous. The discovery that …