Type 2 diabetes accounts for nearly 90% of the approximately 537 million cases of diabetes
worldwide. The number affected is increasing rapidly with alarming trends in children and …

Enormous progress has been made in the last half-century in the management of diseases
closely integrated with excess body weight, such as hypertension, adult-onset diabetes and …

Steady progress over four decades toward understanding the pathogenesis and clinical
consequences of hepatic fibrosis has led to the expectation of effective antifibrotic drugs, yet …

" In this chapter, we introduce some of the very basics that are used throughout the book.
First, we give the definition of a topological space and related notions of open and closed …

Background Interest in the application of machine learning (ML) to the design, conduct, and
analysis of clinical trials has grown, but the evidence base for such applications has not …

Precision medicine is one of the recent and powerful developments in medical care, which
has the potential to improve the traditional symptom-driven practice of medicine, allowing …

The role of physicians has always been to synthesize the data available to them to identify
diagnostic patterns that guide treatment and follow response. Today, increasingly …

'Big data'is massive amounts of information that can work wonders. It has become a topic of
special interest for the past two decades because of a great potential that is hidden in it …

Artificial intelligence and machine learning are poised to influence nearly every aspect of the
human condition, and cardiology is not an exception to this trend. This paper provides a …

Data science is likely to lead to major changes in cardiovascular imaging. Problems with
timing, efficiency, and missed diagnoses occur at all stages of the imaging chain. The …