Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder
N Usui, H Kobayashi, S Shimada - International Journal of Molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …
impairments in social communication, repetitive behaviors, restricted interests, and …
Oxidative stress in autism spectrum disorder—current progress of mechanisms and biomarkers
X Liu, J Lin, H Zhang, NU Khan, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a type of neurodevelopmental disorder that has been
diagnosed in an increasing number of children around the world. Existing data suggest that …
diagnosed in an increasing number of children around the world. Existing data suggest that …
Oxidative stress in autism spectrum disorder
Abstract According to the United States Centers for Disease Control and Prevention (CDC),
as of July 11, 2016, the reported average incidence of children diagnosed with an autism …
as of July 11, 2016, the reported average incidence of children diagnosed with an autism …
[HTML][HTML] Clinical trials of N-acetylcysteine in psychiatry and neurology: a systematic review
N-acetylcysteine (NAC) is recognized for its role in acetaminophen overdose and as a
mucolytic. Over the past decade, there has been growing evidence for the use of NAC in …
mucolytic. Over the past decade, there has been growing evidence for the use of NAC in …
Environmental toxicants and autism spectrum disorders: a systematic review
Although the involvement of genetic abnormalities in autism spectrum disorders (ASD) is
well-accepted, recent studies point to an equal contribution by environmental factors …
well-accepted, recent studies point to an equal contribution by environmental factors …
Alterations in the vaginal microbiome by maternal stress are associated with metabolic reprogramming of the offspring gut and brain
E Jašarević, CL Howerton, CD Howard… - Endocrinology, 2015 - academic.oup.com
The neonate is exposed to the maternal vaginal microbiota during parturition, providing the
primary source for normal gut colonization, host immune maturation, and metabolism. These …
primary source for normal gut colonization, host immune maturation, and metabolism. These …
The role of glutathione redox imbalance in autism spectrum disorder: a review
The role of glutathione in autism spectrum disorder (ASD) is emerging as a major topic, due
to its role in the maintenance of the intracellular redox balance. Several studies have …
to its role in the maintenance of the intracellular redox balance. Several studies have …
Clinical and molecular characteristics of mitochondrial dysfunction in autism spectrum disorder
Autism spectrum disorder (ASD) affects~ 2% of children in the United States. The etiology of
ASD likely involves environmental factors triggering physiological abnormalities in …
ASD likely involves environmental factors triggering physiological abnormalities in …
The multifaceted role of mitochondria in autism spectrum disorder
I Khaliulin, W Hamoudi, H Amal - Molecular psychiatry, 2024 - nature.com
Normal brain functioning relies on high aerobic energy production provided by
mitochondria. Failure to supply a sufficient amount of energy, seen in different brain …
mitochondria. Failure to supply a sufficient amount of energy, seen in different brain …
Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental
disorders that are defined solely on the basis of behavioral observations. Therefore, ASD …
disorders that are defined solely on the basis of behavioral observations. Therefore, ASD …